STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_1753Protein of unknown function DUF1113; COGs: COG4905 membrane protein; InterPro IPR010540; KEGG: cpf:CPF_1398 hypothetical protein; PFAM: Protein of unknown function DUF1113; SPTR: Putative membrane protein; PFAM: Protein of unknown function (DUF1113). (280 aa)    
Predicted Functional Partners:
Sgly_1752
KEGG: ckr:CKR_0541 hypothetical protein; SPTR: Metal dependent phophohydrolase.
     0.984
Sgly_1754
Hypothetical protein.
       0.723
Sgly_1672
Metal dependent phosphohydrolase; InterPro IPR006675: IPR006674: IPR003607; KEGG: ccb:Clocel_0957 hypothetical protein; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: Putative uncharacterized protein; TIGRFAM: HDIG; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG.
     0.721
Sgly_0439
CoA-substrate-specific enzyme activase; COGs: COG3580 conserved hypothetical protein; InterPro IPR002731: IPR018709: IPR008275; KEGG: swo:Swol_1945 putative activator of (R) -2-hydroxyglutaryl-CoA dehydratase; PFAM: Protein of unknown function DUF2229, CoA enzyme activase; ATPase, BadF/BadG/BcrA/BcrD type; SPTR: Putative activator of (R)-2-hydroxyglutaryl-coA dehydratase; TIGRFAM: CoA enzyme activase; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase uncharacterised domain (DUF2229); TIGRFAM: CoA-substrate-specific enzyme activ [...]
 
     0.689
Sgly_3319
CoA-substrate-specific enzyme activase; COGs: COG3580 conserved hypothetical protein; InterPro IPR002731: IPR018709: IPR008275; KEGG: cth:Cthe_1329 putative CoA-substrate-specific enzyme activase; PFAM: Protein of unknown function DUF2229, CoA enzyme activase; ATPase, BadF/BadG/BcrA/BcrD type; SPTR: CoA-substrate-specific enzyme activase; TIGRFAM: CoA enzyme activase; PFAM: 2-hydroxyglutaryl-CoA dehydratase, D-component; BadF/BadG/BcrA/BcrD ATPase family; CoA enzyme activase uncharacterised domain (DUF2229); TIGRFAM: CoA-substrate-specific enzyme activase, putative.
 
     0.683
Sgly_0021
Phospholipase D/Transphosphatidylase; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol; Belongs to the phospholipase D family. Cardiolipin synthase subfamily.
      0.660
Sgly_1751
Transcriptional regulator, TetR family; COGs: COG1309 Transcriptional regulator; InterPro IPR001647; KEGG: cbb:CLD_0061 transcriptional regulator; PFAM: Transcription regulator, TetR-like, DNA-binding, bacterial/archaeal; SPTR: Transcriptional regulator; PFAM: Bacterial regulatory proteins, tetR family.
  
    0.535
Sgly_2568
Helix-turn-helix domain protein; InterPro IPR001387; KEGG: ssa:SSA_0405 XRE family transcriptional regulator; PFAM: Helix-turn-helix type 3; SMART: Helix-turn-helix type 3; SPTR: Predicted transcriptional regulators; PFAM: Helix-turn-helix.
  
     0.480
Sgly_1755
KEGG: dhd:Dhaf_0967 hypothetical protein; SPTR: Putative uncharacterized protein.
       0.439
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.