STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_1863Anti-sigma-factor antagonist; COGs: COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor); InterPro IPR003658: IPR002645; KEGG: dhd:Dhaf_3440 anti-sigma-factor antagonist; PFAM: Sulphate transporter/antisigma-factor antagonist STAS; SPTR: Anti-sigma factor antagonist; TIGRFAM: Anti-sigma factor antagonist; PFAM: STAS domain; TIGRFAM: anti-anti-sigma factor; anti-sigma F factor antagonist. (104 aa)    
Predicted Functional Partners:
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 
 0.991
Sgly_1865
RNA polymerase, sigma subunit, RpoX/SigF; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
  
 0.949
Sgly_1862
Stage V sporulation protein AC; InterPro IPR014203: IPR005562; KEGG: dhd:Dhaf_3439 stage V sporulation protein AC; PFAM: SpoVA; SPTR: Stage V sporulation protein AC; TIGRFAM: Sporulation stage V, protein AC; PFAM: SpoVA protein; TIGRFAM: stage V sporulation protein AC.
 
   
 0.864
Sgly_1861
InterPro IPR010894; KEGG: dhd:Dhaf_3438 stage V sporulation protein AD; PFAM: Stage V sporulation AD; SPTR: Putative uncharacterized protein; TIGRFAM: Stage V sporulation AD; PFAM: Stage V sporulation protein AD (SpoVAD); TIGRFAM: stage V sporulation protein AD.
 
   
 0.847
Sgly_0209
Protein serine/threonine phosphatase; COGs: COG2208 Serine phosphatase RsbU regulator of sigma subunit; InterPro IPR001932: IPR010822; KEGG: dsy:DSY0199 hypothetical protein; PFAM: Sporulation stage II, protein E C-terminal; PRIAM: Phosphoprotein phosphatase; SMART: Protein phosphatase 2C-related; SPTR: Putative uncharacterized protein; PFAM: Stage II sporulation protein E (SpoIIE); TIGRFAM: stage II sporulation protein E.
  
  
 0.837
Sgly_1860
Stage V sporulation protein AE; InterPro IPR014204: IPR005562; KEGG: dhd:Dhaf_3437 stage V sporulation protein AE; PFAM: SpoVA; SPTR: Putative uncharacterized protein; TIGRFAM: Sporulation stage V, protein AE; PFAM: SpoVA protein; TIGRFAM: stage V sporulation protein AE.
 
     0.834
Sgly_1698
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.811
Sgly_2581
InterPro IPR014202; KEGG: dhd:Dhaf_4409 stage II sporulation protein R; PFAM: Sporulation stage II, protein R; SPTR: Putative uncharacterized protein; TIGRFAM: Sporulation stage II, protein R; PFAM: Stage II sporulation protein R (spore_II_R); TIGRFAM: stage II sporulation protein R.
  
   
 0.796
Sgly_0656
RNA polymerase, sigma subunit, RpsG/SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.779
Sgly_1859
InterPro IPR004995; KEGG: dhd:Dhaf_3436 GerA spore germination protein; PFAM: Bacillus/Clostridium GerA spore germination protein; SPTR: Putative uncharacterized protein; PFAM: Bacillus/Clostridium GerA spore germination protein.
 
   
 0.770
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.