STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_1874Response regulator receiver protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process. (270 aa)    
Predicted Functional Partners:
Sgly_1875
SpoIVB peptidase; InterPro IPR014219: IPR008763: IPR001478; KEGG: dhd:Dhaf_3482 stage IV sporulation protein B; PFAM: Peptidase S55, SpoIVB; PRIAM: SpoIVB peptidase; SMART: PDZ/DHR/GLGF; SPTR: Putative uncharacterized protein; TIGRFAM: Peptidase S55, sporulation stage IV, protein B; PFAM: SpoIVB peptidase S55; TIGRFAM: stage IV sporulation protein B.
   
 0.958
Sgly_3296
COGs: COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains; InterPro IPR001789; KEGG: dsy:DSY4941 hypothetical protein; PFAM: Signal transduction response regulator, receiver domain; SMART: Signal transduction response regulator, receiver domain; SPTR: Putative uncharacterized protein; PFAM: Response regulator receiver domain.
  
 
 
0.921
Sgly_2090
Response regulator receiver protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
  
 
0.903
Sgly_1698
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
   
 0.843
Sgly_3266
Sporulation transcriptional regulator SpoIIID; InterPro IPR014208; KEGG: dsy:DSY4887 hypothetical protein; SPTR: Putative uncharacterized protein; TIGRFAM: Sporulation stage III, transcriptional regulator SpoIIID; PFAM: Stage III sporulation protein D; TIGRFAM: sporulation transcriptional regulator SpoIIID.
  
   
 0.838
Sgly_0656
RNA polymerase, sigma subunit, RpsG/SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.836
Sgly_0655
RNA polymerase, sigma 29 subunit, SigE; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.833
Sgly_1861
InterPro IPR010894; KEGG: dhd:Dhaf_3438 stage V sporulation protein AD; PFAM: Stage V sporulation AD; SPTR: Putative uncharacterized protein; TIGRFAM: Stage V sporulation AD; PFAM: Stage V sporulation protein AD (SpoVAD); TIGRFAM: stage V sporulation protein AD.
  
   
 0.828
Sgly_1936
RNA polymerase, sigma 27/28 subunit, RpsK/SigK; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
  
   
 0.825
Sgly_1917
Stage III sporulation protein AA; COGs: COG3854 conserved hypothetical protein; InterPro IPR014217; KEGG: dhd:Dhaf_3516 stage III sporulation protein AA; SPTR: Stage III sporulation protein AA; TIGRFAM: Sporulation stage III, protein AA; TIGRFAM: stage III sporulation protein AA.
 
   
 0.820
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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