STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_1897KEGG: hmo:HM1_2011 4fe-4S ferredoxin, iron-sulfur binding protein, putative; SPTR: 4fe-4S ferredoxin, iron-sulfur binding protein, putative; TIGRFAM: sulfite reductase, subunit A. (330 aa)    
Predicted Functional Partners:
Sgly_1896
Oxidoreductase FAD/NAD(P)-binding domain protein; COGs: COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase; InterPro IPR008333: IPR001433: IPR019480; KEGG: mta:Moth_0816 oxidoreductase FAD/NAD(P)-binding; PFAM: Oxidoreductase FAD/NAD(P)-binding; Oxidoreductase, FAD-binding domain; Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain; SPTR: Oxidoreductase FAD/NAD(P)-binding; PFAM: Oxidoreductase FAD-binding domain; Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B; Oxidoreductase NAD-binding domain.
   0.996
Sgly_1900
Fumarate reductase/succinate dehydrogenase flavoprotein domain protein; COGs: COG1148 Heterodisulfide reductase subunit A and related polyferredoxins; InterPro IPR003953; KEGG: chy:CHY_0930 heterodisulfide reductase, subunit A, selenocysteine-containing; PFAM: Fumarate reductase/succinate dehydrogenase flavoprotein, N-terminal; SPTR: Heterodisulfide reductase, subunit A, selenocysteine-containing; PFAM: FAD binding domain.
 
   0.963
Sgly_1902
4Fe-4S ferredoxin, iron-sulfur binding protein; COGs: COG1150 Heterodisulfide reductase subunit C; KEGG: mta:Moth_0809 4Fe-4S ferredoxin, iron-sulfur binding; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding.
 
   0.962
Sgly_1901
COGs: COG2048 Heterodisulfide reductase subunit B; InterPro IPR004017; KEGG: mta:Moth_0810 hypothetical protein; PFAM: Cysteine-rich domain; PRIAM: CoB--CoM heterodisulfide reductase; SPTR: Putative uncharacterized protein; PFAM: Cysteine-rich domain.
 
 
 0.958
Sgly_1898
KEGG: mta:Moth_0814 4Fe-4S ferredoxin, iron-sulfur binding; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding.
 
     0.946
Sgly_1899
COGs: COG1908 Coenzyme F420-reducing hydrogenase delta subunit; InterPro IPR003813; KEGG: hmo:HM1_2009 methyl-viologen-reducing hydrogenase domain protein, subunit d, putative; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit; SPTR: Methyl-viologen-reducing hydrogenase domain protein, subunit d, putative; PFAM: Methyl-viologen-reducing hydrogenase, delta subunit.
 
 
   0.944
Sgly_0165
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880: IPR019752: IPR019456: IPR011766: IPR 011895; KEGG: dhd:Dhaf_0054 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SPTR: Pyruvate-flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavo [...]
  
  
 0.844
Sgly_2031
COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017; KEGG: dhd:Dhaf_2911 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: Cysteine-rich domain; SPTR: Putative uncharacterized protein; manually curated; PFAM: Cysteine-rich domain.
  
 
 0.756
Sgly_2519
COGs: COG0247 Fe-S oxidoreductase; InterPro IPR004017; KEGG: dhd:Dhaf_4384 protein of unknown function DUF224 cysteine-rich region domain protein; PFAM: Cysteine-rich domain; SPTR: Putative uncharacterized protein; PFAM: Cysteine-rich domain.
  
 
 0.756
pyrK
Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulfur cluster binding domain protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+).
 
   0.505
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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