STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_2055Hypothetical protein; COGs: COG1143 Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I); KEGG: mpi:Mpet_0464 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein; SPTR: 4Fe-4S ferredoxin, iron-sulfur binding. (120 aa)    
Predicted Functional Partners:
Sgly_2057
KEGG: mbn:Mboo_0027 NADH dehydrogenase (ubiquinone), 30 kDa subunit; SPTR: NADH dehydrogenase (Ubiquinone), 30 kDa subunit; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit.
 
 0.993
Sgly_2060
Ech hydrogenase subunit A; COGs: COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter MnhA subunit; InterPro IPR001750; KEGG: mem:Memar_0364 NADH dehydrogenase (quinone); PFAM: NADH:ubiquinone/plastoquinone oxidoreductase; PRIAM: NADH dehydrogenase (quinone); SPTR: Ech hydrogenase subunit A; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus.
 
 
 0.993
Sgly_0127
NADH dehydrogenase (ubiquinone) 30 kDa subunit; COGs: COG3261 Ni Fe-hydrogenase III large subunit; InterPro IPR001268: IPR001501: IPR001135; KEGG: dae:Dtox_0795 NADH dehydrogenase (ubiquinone) 30 kDa subunit; PFAM: NADH:ubiquinone oxidoreductase, 30kDa subunit; Nickel-dependent hydrogenase, large subunit; NADH-quinone oxidoreductase, subunit D; SPTR: Similar to membrane-bound [NiFe]-hydrogenase-3, large subunit (Chain E); PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit; Nickel-dependent hydrogenase.
 
 0.988
Sgly_2058
COGs: COG3260 Ni Fe-hydrogenase III small subunit; InterPro IPR006137; KEGG: mpi:Mpet_0467 NADH ubiquinone oxidoreductase 20 kDa subunit; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH ubiquinone oxidoreductase, 20 kDa subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
 
 
 0.987
Sgly_2056
COGs: COG3261 Ni Fe-hydrogenase III large subunit; InterPro IPR001501: IPR001135; KEGG: cpy:Cphy_1734 NADH-ubiquinone oxidoreductase chain 49kDa; PFAM: NADH-quinone oxidoreductase, subunit D; Nickel-dependent hydrogenase, large subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH-ubiquinone oxidoreductase chain 49kDa; PFAM: Respiratory-chain NADH dehydrogenase, 49 Kd subunit; Nickel-dependent hydrogenase.
 
 
 0.986
Sgly_2059
COGs: COG0650 Formate hydrogenlyase subunit 4; InterPro IPR001694; KEGG: mem:Memar_0363 respiratory-chain NADH dehydrogenase, subunit 1; PFAM: NADH:ubiquinone oxidoreductase, subunit 1; SPTR: Ech hydrogenase subunit B; PFAM: NADH dehydrogenase.
 
 
 0.978
Sgly_2686
NAD(P)-dependent iron-only hydrogenase diaphorase component flavoprotein; COGs: COG1894 NADH:ubiquinone oxidoreductase NADH-binding (51 kD) subunit; InterPro IPR011538: IPR019554: IPR019575; KEGG: dsy:DSY3970 NADH dehydrogenase I chain F; PFAM: NADH:ubiquinone oxidoreductase, 51kDa subunit; Soluble ligand binding domain; NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding; PRIAM: NADH dehydrogenase (quinone); SPTR: NADH dehydrogenase I chain F; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4Fe-4S binding domain; Respiratory-chain NADH dehydrogenase 24 K [...]
 
 0.949
Sgly_0165
COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR002880: IPR019752: IPR019456: IPR011766: IPR 011895; KEGG: dhd:Dhaf_0054 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase, catalytic domain; Pyruvate-flavodoxin oxidoreductase, EKR domain; Thiamine pyrophosphate enzyme, C-terminal TPP-binding; PRIAM: Pyruvate dehydrogenase (NADP(+)); SPTR: Pyruvate-flavodoxin oxidoreductase; TIGRFAM: Pyruvate-flavo [...]
  
 
 0.941
Sgly_0128
NADH dehydrogenase (quinone); COGs: COG3260 Ni Fe-hydrogenase III small subunit; InterPro IPR006137; KEGG: cce:Ccel_1686 NADH ubiquinone oxidoreductase 20 kDa subunit; PFAM: NADH:ubiquinone oxidoreductase-like, 20kDa subunit; PRIAM: NADH dehydrogenase (quinone); SPTR: Strongly similar to membrane-bound [NiFe]-hydrogenase-3, small subunit (Chain G); PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
 
 
 0.927
Sgly_1112
KEGG: ssm:Spirs_2834 hypothetical protein; SPTR: Sarcosine oxidase, subunit alpha.
  
 0.925
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.