STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
menGDemethylmenaquinone methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2). (238 aa)    
Predicted Functional Partners:
Sgly_1255
NAD(P)H dehydrogenase (quinone); COGs: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: sga:GALLO_0139 putative NADPH-quinone reductase; PFAM: Flavodoxin-like fold; SPTR: Putative NADPH-quinone reductase; PFAM: Flavodoxin-like fold.
  
  
  0.912
Sgly_3171
KEGG: lpp:lpp0028 hypothetical protein; SPTR:2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquino lhydroxylase; PFAM: Ubiquinone biosynthesis protein COQ7.
   
 
 0.904
Sgly_0889
NAD(P)H dehydrogenase (quinone); COGs: COG2249 Putative NADPH-quinone reductase (modulator of drug activity B); InterPro IPR003680; KEGG: ele:Elen_0321 NAD(P)H dehydrogenase (quinone); PFAM: Flavodoxin-like fold; SPTR: NAD(P)H dehydrogenase, quinone family; PFAM: Flavodoxin-like fold.
     
  0.900
Sgly_1598
KpsF/GutQ family protein; COGs: COG0794 sugar phosphate isomerase involved in capsule formation; InterPro IPR004800: IPR001347: IPR000644; KEGG: slt:Slit_0441 KpsF/GutQ family protein; PFAM: Sugar isomerase (SIS); Cystathionine beta-synthase, core; PRIAM: Arabinose-5-phosphate isomerase; SPTR: Putative uncharacterized protein; TIGRFAM: KpsF/GutQ; PFAM: CBS domain; SIS domain; TIGRFAM: KpsF/GutQ family protein; Belongs to the SIS family. GutQ/KpsF subfamily.
 
 
   0.767
Sgly_1805
COGs: COG0043 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylase; InterPro IPR002830; KEGG: tjr:TherJR_2498 UbiD family decarboxylase; PFAM: Carboxylyase-related; SPTR: UbiD family decarboxylase; TIGRFAM: Carboxylyase-related; PFAM: 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; TIGRFAM: UbiD family decarboxylases; Belongs to the UbiD family.
 
  
 0.748
Sgly_1713
Trans-hexaprenyltranstransferase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: dsy:DSY2232 hypothetical protein; PFAM: Polyprenyl synthetase; PRIAM: Trans-hexaprenyltranstransferase; SPTR: Putative uncharacterized protein; PFAM: Polyprenyl synthetase; TIGRFAM: heptaprenyl diphosphate synthase component II; Belongs to the FPP/GGPP synthase family.
 
  
 0.663
Sgly_1973
COGs: COG0438 Glycosyltransferase; InterPro IPR001296; KEGG: dhd:Dhaf_3604 glycosyl transferase group 1; PFAM: Glycosyl transferase, group 1; SPTR: Putative uncharacterized protein; PFAM: Glycosyl transferases group 1.
 
      0.610
Sgly_2178
Late competence development protein ComFB; InterPro IPR019657; KEGG: dhd:Dhaf_3069 putative ComF operon protein; PFAM: Late competence development protein ComFB; SPTR: Putative uncharacterized protein; PFAM: Late competence development protein ComFB.
       0.506
Sgly_2176
PhoH family protein; COGs: COG1875 ATPase related to phosphate starvation-inducible protein PhoH; InterPro IPR006596: IPR003714; KEGG: cth:Cthe_1304 PhoH-like protein; PFAM: PhoH-like protein; SMART: Nucleotide binding protein, PINc; SPTR: PhoH-like protein; PFAM: PhoH-like protein.
       0.484
mqnE
Putative menaquinone biosynthesis protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate.
     
 0.456
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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