STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_2472Rod shape-determining protein MreB; COGs: COG1077 Actin-like ATPase involved in cell morphogenesis; InterPro IPR004753; KEGG: dhd:Dhaf_4351 rod shape-determining protein MreB; PFAM: Cell shape determining protein MreB/Mrl; SPTR: Putative uncharacterized protein; TIGRFAM: Cell shape determining protein MreB/Mrl; PFAM: MreB/Mbl protein; TIGRFAM: cell shape determining protein, MreB/Mrl family. (338 aa)    
Predicted Functional Partners:
Sgly_2471
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
 
 0.995
Sgly_2469
Peptidoglycan glycosyltransferase; COGs: COG0768 Cell division protein FtsI/penicillin-binding protein 2; InterPro IPR005311: IPR001460: IPR017790; KEGG: dhd:Dhaf_4348 penicillin-binding protein 2; PFAM: Penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PRIAM: Peptidoglycan glycosyltransferase; SPTR: Putative uncharacterized protein; TIGRFAM: Penicillin-binding protein 2; PFAM: Penicillin binding protein transpeptidase domain; Penicillin-binding Protein dimerisation domain; TIGRFAM: penicillin-binding protein 2.
 
 0.962
Sgly_2216
Transcriptional regulator, XRE family; COGs: COG1426 conserved hypothetical protein; KEGG: dhd:Dhaf_3128 transcriptional regulator, XRE family; SPTR: Transcriptional regulator, XRE family.
  
 
 0.889
rodA
Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
 
 0.844
Sgly_2470
InterPro IPR007227; KEGG: dhd:Dhaf_4349 rod shape-determining protein MreD; PFAM: Cell shape-determining protein MreD; SPTR: Putative uncharacterized protein; TIGRFAM: Cell shape-determining protein MreD; PFAM: rod shape-determining protein MreD; TIGRFAM: rod shape-determining protein MreD.
  
  
 0.844
Sgly_2473
COGs: COG2003 DNA repair protein; InterPro IPR001405; KEGG: dhd:Dhaf_4352 DNA repair protein RadC; PFAM: Uncharacterised protein family, RadC-like; SPTR: UPF0758 protein Dhaf_4352; TIGRFAM: Uncharacterised protein family, RadC-like; manually curated; PFAM: Protein of unknown function (DUF2466); TIGRFAM: DNA repair protein radc; Belongs to the UPF0758 family.
  
  
 0.800
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.775
Sgly_2468
Septum site-determining protein MinD; COGs: COG2894 Septum formation inhibitor-activating ATPase; InterPro IPR010223; KEGG: dhd:Dhaf_4346 septum site-determining protein MinD; SPTR: Putative uncharacterized protein; TIGRFAM: Septum site-determining protein MinD; PFAM: CobQ/CobB/MinD/ParA nucleotide binding domain; TIGRFAM: septum site-determining protein MinD.
  
 
 0.692
Sgly_2474
Septum formation protein Maf; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
  
 0.690
Sgly_1693
Cell division-specific peptidoglycan biosynthesis regulator FtsW; COGs: COG0772 Bacterial cell division membrane protein; InterPro IPR013437: IPR001182; KEGG: dsy:DSY2254 hypothetical protein; PFAM: Cell cycle protein; SPTR: Putative uncharacterized protein; TIGRFAM: Cell division protein FtsW; PFAM: Cell cycle protein; TIGRFAM: cell division protein FtsW; Belongs to the SEDS family.
 
 
 0.595
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.