STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_2573InterPro IPR010178; KEGG: thx:Thet_1883 integral membrane protein TIGR01906; PFAM: Integral membrane protein 1906; SPTR: Putative uncharacterized protein; TIGRFAM: Integral membrane protein 1906; PFAM: Protein of unknown function (DUF1461); TIGRFAM: integral membrane protein TIGR01906. (234 aa)    
Predicted Functional Partners:
rph
RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.
       0.709
Sgly_2574
COGs: COG4122 O-methyltransferase; InterPro IPR002935; KEGG: dhd:Dhaf_4391 O-methyltransferase family 3; PFAM: O-methyltransferase, family 3; SPTR: O-methyltransferase family 3; PFAM: O-methyltransferase.
 
     0.669
Sgly_2571
Nucleoside-triphosphatase rdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
       0.614
Sgly_2575
RNA methylase, NOL1/NOP2/sun family; COGs: COG0144 tRNA and rRNA cytosine-C5-methylase; InterPro IPR001678: IPR011023; KEGG: gym:GYMC10_4583 Fmu (Sun) domain protein; PFAM: Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p; SPTR: NOL1/NOP2/sun family protein; TIGRFAM: Nop2p; PFAM: NOL1/NOP2/sun family; TIGRFAM: NOL1/NOP2/sun family putative RNA methylase.
       0.572
recX
Regulatory protein recX; Modulates RecA activity; Belongs to the RecX family.
  
     0.430
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.