STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_2697Domain of unknown function DUF1727; COGs: COG0769 UDP-N-acetylmuramyl tripeptide synthase; InterPro IPR013221: IPR013564; KEGG: dsy:DSY4019 hypothetical protein; PFAM: Domain of unknown function DUF1727; Mur ligase, central; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF1727); Mur ligase middle domain. (466 aa)    
Predicted Functional Partners:
Sgly_2696
COGs: COG3442 glutamine amidotransferase; InterPro IPR011698; KEGG: dhd:Dhaf_1346 CobB/CobQ domain protein glutamine amidotransferase; PFAM: CobB/CobQ-like glutamine amidotransferase; SPTR: Putative uncharacterized protein; PFAM: CobB/CobQ-like glutamine amidotransferase domain.
 0.999
murG
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
  
 0.950
Sgly_3298
Methicillin resistance protein; COGs: COG2348 Uncharacterized protein involved in methicillin resistance; InterPro IPR003447; KEGG: dhd:Dhaf_4843 methicillin resistance protein; PFAM: Methicillin resistance protein; SPTR: Methicillin resistance protein; PFAM: FemAB family.
  
 
 0.909
murF
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
  
  
0.685
murD
UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family.
  
  
 0.546
pheT
COGs: COG0072 Phenylalanyl-tRNA synthetase beta subunit; HAMAP: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; InterPro IPR002547: IPR005146: IPR005147: IPR005121: IPR 004532; KEGG: dsy:DSY0272 phenylalanyl-tRNA synthetase subunit beta; PFAM: B3/B4 tRNA-binding domain; tRNA-binding domain; tRNA synthetase, B5; Phenylalanyl-tRNA synthetase, beta subunit, ferrodoxin-fold anticodon-binding; SPTR: Putative uncharacterized protein; TIGRFAM: Phenylalanyl-tRNA synthetase, class IIc, beta subunit, bacterial; PFAM: tRNA synthetase B5 domain; Ferredoxin-fold anticodon binding [...]
 
   
 0.502
Sgly_1740
Glycosyl transferase, family 4, conserved region-containing protein; COGs: COG0472 UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase; InterPro IPR018481; KEGG: dhd:Dhaf_2406 glycosyl transferase family 4; PFAM: Glycosyl transferase, family 4, conserved region; SPTR: Putative uncharacterized protein; PFAM: Glycosyl transferase family 4.
 
  
 0.500
Sgly_2694
Transcriptional modulator of MazE/toxin, MazF; Toxic component of a type II toxin-antitoxin (TA) system.
       0.483
Sgly_2695
KEGG: dhd:Dhaf_1347 putative transcriptional regulator, CopG family; SPTR: Putative uncharacterized protein.
       0.482
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family.
  
  
 0.472
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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