node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sgly_1687 | Sgly_2370 | Sgly_1687 | Sgly_2370 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | COGs: COG0077 Prephenate dehydratase; InterPro IPR001086: IPR002912; KEGG: clj:CLJU_c29130 bifunctional chorismate mutase/prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; PRIAM: Prephenate dehydratase; SPTR: Bifunctional chorismate mutase/ prephenate dehydratase; PFAM: Prephenate dehydratase. | 0.922 |
Sgly_1687 | Sgly_2868 | Sgly_1687 | Sgly_2868 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006805: IPR015890: IPR005802; KEGG: amt:Amet_2158 para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; PRIAM: Anthranilate synthase; SPTR: Para-aminobenzoate synthase, subunit I; TIGRFAM: Para-aminobenzoate synthase, component I; PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade. | 0.810 |
Sgly_1687 | Sgly_2874 | Sgly_1687 | Sgly_2874 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterPro IPR000991: IPR006221; KEGG: cth:Cthe_0874 anthranilate synthase, component II; PFAM: Glutamine amidotransferase class-I, C-terminal; PRIAM: Anthranilate synthase; SPTR: Anthranilate synthase, component II; TIGRFAM: Glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. | 0.910 |
Sgly_1687 | aroC | Sgly_1687 | Sgly_2371 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.946 |
Sgly_1687 | trpE | Sgly_1687 | Sgly_2875 | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.905 |
Sgly_2370 | Sgly_1687 | Sgly_2370 | Sgly_1687 | COGs: COG0077 Prephenate dehydratase; InterPro IPR001086: IPR002912; KEGG: clj:CLJU_c29130 bifunctional chorismate mutase/prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; PRIAM: Prephenate dehydratase; SPTR: Bifunctional chorismate mutase/ prephenate dehydratase; PFAM: Prephenate dehydratase. | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | 0.922 |
Sgly_2370 | Sgly_2868 | Sgly_2370 | Sgly_2868 | COGs: COG0077 Prephenate dehydratase; InterPro IPR001086: IPR002912; KEGG: clj:CLJU_c29130 bifunctional chorismate mutase/prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; PRIAM: Prephenate dehydratase; SPTR: Bifunctional chorismate mutase/ prephenate dehydratase; PFAM: Prephenate dehydratase. | COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006805: IPR015890: IPR005802; KEGG: amt:Amet_2158 para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; PRIAM: Anthranilate synthase; SPTR: Para-aminobenzoate synthase, subunit I; TIGRFAM: Para-aminobenzoate synthase, component I; PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade. | 0.860 |
Sgly_2370 | Sgly_2874 | Sgly_2370 | Sgly_2874 | COGs: COG0077 Prephenate dehydratase; InterPro IPR001086: IPR002912; KEGG: clj:CLJU_c29130 bifunctional chorismate mutase/prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; PRIAM: Prephenate dehydratase; SPTR: Bifunctional chorismate mutase/ prephenate dehydratase; PFAM: Prephenate dehydratase. | COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterPro IPR000991: IPR006221; KEGG: cth:Cthe_0874 anthranilate synthase, component II; PFAM: Glutamine amidotransferase class-I, C-terminal; PRIAM: Anthranilate synthase; SPTR: Anthranilate synthase, component II; TIGRFAM: Glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. | 0.937 |
Sgly_2370 | aroC | Sgly_2370 | Sgly_2371 | COGs: COG0077 Prephenate dehydratase; InterPro IPR001086: IPR002912; KEGG: clj:CLJU_c29130 bifunctional chorismate mutase/prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; PRIAM: Prephenate dehydratase; SPTR: Bifunctional chorismate mutase/ prephenate dehydratase; PFAM: Prephenate dehydratase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.992 |
Sgly_2370 | trpA | Sgly_2370 | Sgly_2869 | COGs: COG0077 Prephenate dehydratase; InterPro IPR001086: IPR002912; KEGG: clj:CLJU_c29130 bifunctional chorismate mutase/prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; PRIAM: Prephenate dehydratase; SPTR: Bifunctional chorismate mutase/ prephenate dehydratase; PFAM: Prephenate dehydratase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.402 |
Sgly_2370 | trpC | Sgly_2370 | Sgly_2872 | COGs: COG0077 Prephenate dehydratase; InterPro IPR001086: IPR002912; KEGG: clj:CLJU_c29130 bifunctional chorismate mutase/prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; PRIAM: Prephenate dehydratase; SPTR: Bifunctional chorismate mutase/ prephenate dehydratase; PFAM: Prephenate dehydratase. | COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798; KEGG: cth:Cthe_0872 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Putative uncharacterized protein; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. | 0.500 |
Sgly_2370 | trpD | Sgly_2370 | Sgly_2873 | COGs: COG0077 Prephenate dehydratase; InterPro IPR001086: IPR002912; KEGG: clj:CLJU_c29130 bifunctional chorismate mutase/prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; PRIAM: Prephenate dehydratase; SPTR: Bifunctional chorismate mutase/ prephenate dehydratase; PFAM: Prephenate dehydratase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.464 |
Sgly_2370 | trpE | Sgly_2370 | Sgly_2875 | COGs: COG0077 Prephenate dehydratase; InterPro IPR001086: IPR002912; KEGG: clj:CLJU_c29130 bifunctional chorismate mutase/prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; PRIAM: Prephenate dehydratase; SPTR: Bifunctional chorismate mutase/ prephenate dehydratase; PFAM: Prephenate dehydratase. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.932 |
Sgly_2370 | trpF | Sgly_2370 | Sgly_2871 | COGs: COG0077 Prephenate dehydratase; InterPro IPR001086: IPR002912; KEGG: clj:CLJU_c29130 bifunctional chorismate mutase/prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; PRIAM: Prephenate dehydratase; SPTR: Bifunctional chorismate mutase/ prephenate dehydratase; PFAM: Prephenate dehydratase. | COGs: COG0135 Phosphoribosylanthranilate isomerase; InterPro IPR001240; KEGG: cth:Cthe_0871 phosphoribosylanthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); PRIAM: Phosphoribosylanthranilate isomerase; SPTR: N-(5'-phosphoribosyl)anthranilate isomerase; PFAM: N-(5'phosphoribosyl)anthranilate (PRA) isomerase; Belongs to the TrpF family. | 0.453 |
Sgly_2868 | Sgly_1687 | Sgly_2868 | Sgly_1687 | COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006805: IPR015890: IPR005802; KEGG: amt:Amet_2158 para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; PRIAM: Anthranilate synthase; SPTR: Para-aminobenzoate synthase, subunit I; TIGRFAM: Para-aminobenzoate synthase, component I; PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade. | Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. | 0.810 |
Sgly_2868 | Sgly_2370 | Sgly_2868 | Sgly_2370 | COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006805: IPR015890: IPR005802; KEGG: amt:Amet_2158 para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; PRIAM: Anthranilate synthase; SPTR: Para-aminobenzoate synthase, subunit I; TIGRFAM: Para-aminobenzoate synthase, component I; PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade. | COGs: COG0077 Prephenate dehydratase; InterPro IPR001086: IPR002912; KEGG: clj:CLJU_c29130 bifunctional chorismate mutase/prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; PRIAM: Prephenate dehydratase; SPTR: Bifunctional chorismate mutase/ prephenate dehydratase; PFAM: Prephenate dehydratase. | 0.860 |
Sgly_2868 | Sgly_2874 | Sgly_2868 | Sgly_2874 | COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006805: IPR015890: IPR005802; KEGG: amt:Amet_2158 para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; PRIAM: Anthranilate synthase; SPTR: Para-aminobenzoate synthase, subunit I; TIGRFAM: Para-aminobenzoate synthase, component I; PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade. | COGs: COG0512 Anthranilate/para-aminobenzoate synthase component II; InterPro IPR000991: IPR006221; KEGG: cth:Cthe_0874 anthranilate synthase, component II; PFAM: Glutamine amidotransferase class-I, C-terminal; PRIAM: Anthranilate synthase; SPTR: Anthranilate synthase, component II; TIGRFAM: Glutamine amidotransferase of anthranilate synthase; PFAM: Glutamine amidotransferase class-I; TIGRFAM: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase. | 0.999 |
Sgly_2868 | aroC | Sgly_2868 | Sgly_2371 | COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006805: IPR015890: IPR005802; KEGG: amt:Amet_2158 para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; PRIAM: Anthranilate synthase; SPTR: Para-aminobenzoate synthase, subunit I; TIGRFAM: Para-aminobenzoate synthase, component I; PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.901 |
Sgly_2868 | trpA | Sgly_2868 | Sgly_2869 | COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006805: IPR015890: IPR005802; KEGG: amt:Amet_2158 para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; PRIAM: Anthranilate synthase; SPTR: Para-aminobenzoate synthase, subunit I; TIGRFAM: Para-aminobenzoate synthase, component I; PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.978 |
Sgly_2868 | trpB-2 | Sgly_2868 | Sgly_2870 | COGs: COG0147 Anthranilate/para-aminobenzoate synthase component I; InterPro IPR006805: IPR015890: IPR005802; KEGG: amt:Amet_2158 para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding, C-terminal; Anthranilate synthase component I, N-terminal; PRIAM: Anthranilate synthase; SPTR: Para-aminobenzoate synthase, subunit I; TIGRFAM: Para-aminobenzoate synthase, component I; PFAM: Anthranilate synthase component I, N terminal region; chorismate binding enzyme; TIGRFAM: aminodeoxychorismate synthase, component I, bacterial clade. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.918 |