STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
moaCGTP cyclohydrolase subunit MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (158 aa)    
Predicted Functional Partners:
moaA
GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
 
 0.999
Sgly_3076
COGs: COG0521 Molybdopterin biosynthesis protein; InterPro IPR001453: IPR020817; KEGG: hmo:HM1_0061 molybdenum cofactor biosynthesis protein, putative; PFAM: Molybdopterin binding; SPTR: Molybdenum cofactor biosynthesis protein, putative; TIGRFAM: Molybdenum cofactor synthesis; PFAM: Probable molybdopterin binding domain; TIGRFAM: molybdenum cofactor synthesis domain.
  
 0.998
Sgly_3075
COGs: COG1763 Molybdopterin-guanine dinucleotide biosynthesis protein; InterPro IPR004435; KEGG: dae:Dtox_3499 molybdopterin-guanine dinucleotide biosynthesis protein B; SPTR: Molybdopterin-guanine dinucleotide biosynthesis protein B; TIGRFAM: Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB), conserved domain; PFAM: Molybdopterin guanine dinucleotide synthesis protein B; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein MobB.
  
 0.988
Sgly_3074
MOSC domain containing protein; COGs: COG2258 conserved hypothetical protein; InterPro IPR005302; KEGG: cbe:Cbei_1991 MOSC domain-containing protein; PFAM: Molybdenum cofactor sulfurase, C-terminal; SPTR: MOSC domain containing protein; PFAM: MOSC domain.
  
 0.987
Sgly_3080
Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
  
 0.967
Sgly_3079
Molybdopterin binding domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.898
trpC
COGs: COG0134 Indole-3-glycerol phosphate synthase; InterPro IPR013798; KEGG: cth:Cthe_0872 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; PRIAM: Indole-3-glycerol-phosphate synthase; SPTR: Putative uncharacterized protein; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
    
 0.771
Sgly_3084
Indolepyruvate ferredoxin oxidoreductase, alpha subunit; Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.
  
    0.750
mobA
Molybdopterin-guanine dinucleotide biosynthesis protein A; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.
 
   
 0.701
Sgly_0469
Molybdate ABC transporter, inner membrane subunit; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.
 
   
 0.685
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.