STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_3167NAD(P)H dehydrogenase (quinone); COGs: COG0431 flavoprotein; InterPro IPR005025; KEGG: rci:RRC291 NADPH-dependent FMN reductase; PFAM: NADPH-dependent FMN reductase; PRIAM: NAD(P)H dehydrogenase (quinone); SPTR: NADPH dehydrogenase quinone:NADPH dependent FMN reductase; PFAM: NADPH-dependent FMN reductase. (190 aa)    
Predicted Functional Partners:
Sgly_3166
Protein of unknown function DUF307; InterPro IPR005185; KEGG: rca:Rcas_2965 hypothetical protein; PFAM: Protein of unknown function DUF307; SPTR: Putative uncharacterized protein; PFAM: Domain of unknown function (DUF307).
       0.773
Sgly_3168
COGs: COG0589 Universal stress protein UspA and related nucleotide-binding protein; InterPro IPR006016; KEGG: dhd:Dhaf_0384 UspA domain protein; PFAM: UspA; SPTR: Putative uncharacterized protein; PFAM: Universal stress protein family.
       0.701
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.571
msrA
Peptide methionine sulfoxide reductase msrB; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.549
mqnB
Futalosine nucleosidase; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).
       0.488
Sgly_1736
CoA-disulfide reductase; COGs: COG0446 NAD(FAD)-dependent dehydrogenase; InterPro IPR013027: IPR004099: IPR001763; KEGG: ttm:Tthe_0249 FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rhodanese-like; PRIAM: CoA-disulfide reductase; SMART: Rhodanese-like; SPTR: Putative uncharacterized protein; PFAM: Pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Rhodanese-like domain.
     
 0.477
mqnD
Hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.
       0.463
Sgly_3171
KEGG: lpp:lpp0028 hypothetical protein; SPTR:2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquino lhydroxylase; PFAM: Ubiquinone biosynthesis protein COQ7.
       0.454
Sgly_1206
2,4-dienoyl-CoA reductase (NADPH); COGs: COG1902 NADH:flavin oxidoreductase Old Yellow Enzyme family; InterPro IPR001155: IPR013027; KEGG: tte:TTE2131 NADH:flavin oxidoreductase; PFAM: NADH:flavin oxidoreductase/NADH oxidase, N-terminal; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; PRIAM: 2,4-dienoyl-CoA reductase (NADPH); SPTR: NADH:flavin oxidoreductase; PFAM: Pyridine nucleotide-disulphide oxidoreductase; NADH:flavin oxidoreductase / NADH oxidase family.
     
 0.442
Sgly_0507
Sulfate adenylyltransferase subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
   
  
 0.441
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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