STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sgly_3183Metal dependent phosphohydrolase; COGs: COG2206 HD-GYP domain; InterPro IPR006674: IPR003607: IPR006675; KEGG: dhd:Dhaf_0175 metal dependent phosphohydrolase; PFAM: Metal-dependent phosphohydrolase, HD subdomain; SMART: Metal-dependent phosphohydrolase, HD domain; SPTR: Putative uncharacterized protein; TIGRFAM: HDIG; PFAM: HD domain; TIGRFAM: uncharacterized domain HDIG. (251 aa)    
Predicted Functional Partners:
Sgly_3307
Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: ddf:DEFDS_0866 hypothetical protein; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: Putative uncharacterized protein; TIGRFAM: Diguanylate cyclase, predicted; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
   0.811
Sgly_1411
Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160; KEGG: ssm:Spirs_4224 diguanylate cyclase; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase; TIGRFAM: Diguanylate cyclase, predicted; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
   0.773
Sgly_3073
Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: slp:Slip_0516 diguanylate cyclase; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase; TIGRFAM: Diguanylate cyclase, predicted; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
   0.757
Sgly_0151
Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: slp:Slip_1139 diguanylate cyclase/phosphodiesterase with GAF sensor; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase/phosphodiesterase; TIGRFAM: Diguanylate cyclase, predicted; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
 0.746
Sgly_0118
Diguanylate cyclase; COGs: COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain; InterPro IPR000160; KEGG: abo:ABO_1262 GGDEF domain-containing protein; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: GGDEF domain protein; TIGRFAM: Diguanylate cyclase, predicted; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
     0.737
Sgly_1584
Diguanylate cyclase; COGs: COG2199 FOG: GGDEF domain; InterPro IPR000160; KEGG: bse:Bsel_2945 diguanylate cyclase; PFAM: Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase; TIGRFAM: Diguanylate cyclase, predicted; PFAM: GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
  
   0.698
Sgly_2709
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR000014: IPR001610: IPR000160: IPR001633: IPR 013767; KEGG: tjr:TherJR_0997 diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS fold; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAC motif; PAS; SPTR: Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); TIGRFAM: Diguanylate cyclase [...]
 
 
 0.694
Sgly_0119
Diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR000160: IPR001633; KEGG: cdf:CD1476 putative signaling protein; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; SPTR: Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S); TIGRFAM: Diguanylate cyclase, predicted; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 
 0.685
Sgly_1996
Diguanylate cyclase/phosphodiesterase; COGs: COG2200 FOG: EAL domain; InterPro IPR000160: IPR001633: IPR004010; KEGG: ckr:CKR_1648 hypothetical protein; PFAM: Diguanylate phosphodiesterase, predicted; Cache; Diguanylate cyclase, predicted; SMART: Diguanylate cyclase, predicted; Diguanylate phosphodiesterase, predicted; SPTR: Putative uncharacterized protein; TIGRFAM: Diguanylate cyclase, predicted; PFAM: EAL domain; GGDEF domain; TIGRFAM: diguanylate cyclase (GGDEF) domain.
 
 0.667
Sgly_2935
Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); COGs: COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain; InterPro IPR013655: IPR000160: IPR001633: IPR001610: IPR 000014; KEGG: tte:TTE1081 diguanylate cyclase/phosphodiesterase; PFAM: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAS fold-3; PRIAM: Diguanylate kinase; SMART: Diguanylate phosphodiesterase, predicted; Diguanylate cyclase, predicted; PAC motif; SPTR: PAS fold family protein; TIGRFAM: Diguanylate cyclase, predicted; PAS; PFAM: EAL domain; GGDE [...]
  
   
 0.635
Your Current Organism:
Syntrophobotulus glycolicus
NCBI taxonomy Id: 645991
Other names: S. glycolicus DSM 8271, Syntrophobotulus glycolicus DSM 8271, Syntrophobotulus glycolicus str. DSM 8271, Syntrophobotulus glycolicus strain DSM 8271
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.