STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdxYPyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. (287 aa)    
Predicted Functional Partners:
pdxH
Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).
    
 0.954
pdxY-2
Pyridoxal kinase; Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP.
  
  
 
0.929
pdxJ
Pyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.
     
 0.929
thiE
Phosphomethylpyrimidine kinase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
   
 
 0.786
OHY88487.1
YggS family pyridoxal phosphate enzyme; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
  
 0.603
OHY90413.1
GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.559
OHY89707.1
Kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.534
OHY96789.1
DUF429 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.444
OHY96940.1
UMP phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.415
Your Current Organism:
Aeromonas sobria
NCBI taxonomy Id: 646
Other names: A. sobria, ATCC 43979, Aeromonas hybridization group 7 (HG7), Aeromonas sp. TH002, Aeromonas sp. TH004, Aeromonas sp. TH005, Aeromonas sp. TH018, Aeromonas sp. TH032, Aeromonas sp. TH035, Aeromonas sp. TH037, Aeromonas sp. TH040, Aeromonas sp. TH070, Aeromonas sp. TH082, Aeromonas sp. TH103, Aeromonas sp. TH112, Aeromonas sp. TH116, Aeromonas sp. TH119, CCUG 14830, CECT 4245, CIP 74.33, DSM 19176, JCM 2139, LMG 3783, LMG:3783, NCTC 12979, strain 208
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