node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EHP00_1715 | EHP00_251 | A0A1W0E7P2 | A0A1W0E6J9 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Eukaryotic core primase Large subunit. | 0.982 |
EHP00_1715 | MCM7 | A0A1W0E7P2 | A0A1W0E5D6 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.902 |
EHP00_1715 | POL2 | A0A1W0E7P2 | A0A1W0E5U1 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. | 0.940 |
EHP00_1715 | Prim1 | A0A1W0E7P2 | A0A1W0E3V5 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Prim1. | 0.954 |
EHP00_1715 | RAD51A | A0A1W0E7P2 | A0A1W0E7A1 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. | 0.929 |
EHP00_1715 | RNASEH2A | A0A1W0E7P2 | A0A1W0E6N6 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.913 |
EHP00_1715 | TS-1 | A0A1W0E7P2 | A0A1W0E382 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | TS-1. | 0.861 |
EHP00_1715 | dinB | A0A1W0E7P2 | A0A1W0E9F5 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | DinB. | 0.987 |
EHP00_1715 | orc1-2 | A0A1W0E7P2 | A0A1W0E968 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | Orc1. | 0.580 |
EHP00_1715 | rqh1 | A0A1W0E7P2 | A0A1W0E4R0 | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.861 |
EHP00_251 | EHP00_1715 | A0A1W0E6J9 | A0A1W0E7P2 | Eukaryotic core primase Large subunit. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.982 |
EHP00_251 | MCM7 | A0A1W0E6J9 | A0A1W0E5D6 | Eukaryotic core primase Large subunit. | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | 0.931 |
EHP00_251 | POL2 | A0A1W0E6J9 | A0A1W0E5U1 | Eukaryotic core primase Large subunit. | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. | 0.942 |
EHP00_251 | Prim1 | A0A1W0E6J9 | A0A1W0E3V5 | Eukaryotic core primase Large subunit. | Prim1. | 0.999 |
EHP00_251 | RAD51A | A0A1W0E6J9 | A0A1W0E7A1 | Eukaryotic core primase Large subunit. | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. | 0.601 |
EHP00_251 | RNASEH2A | A0A1W0E6J9 | A0A1W0E6N6 | Eukaryotic core primase Large subunit. | Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. | 0.802 |
EHP00_251 | TS-1 | A0A1W0E6J9 | A0A1W0E382 | Eukaryotic core primase Large subunit. | TS-1. | 0.657 |
EHP00_251 | orc1-2 | A0A1W0E6J9 | A0A1W0E968 | Eukaryotic core primase Large subunit. | Orc1. | 0.931 |
EHP00_251 | rqh1 | A0A1W0E6J9 | A0A1W0E4R0 | Eukaryotic core primase Large subunit. | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.518 |
MCM7 | EHP00_1715 | A0A1W0E5D6 | A0A1W0E7P2 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.902 |