STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Cooccurrence
Coexpression
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[Homology]
Score
AFM39397.1Formate hydrogenlyase subunit 3/multisubunit Na+/H+ antiporter, MnhD subunit; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains. (490 aa)    
Predicted Functional Partners:
AFM39398.1
Ni,Fe-hydrogenase III large subunit; PFAM: Respiratory-chain NADH dehydrogenase, 30 Kd subunit; Respiratory-chain NADH dehydrogenase, 49 Kd subunit.
 
 
 0.999
AFM39399.1
Ni,Fe-hydrogenase III small subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit.
 
 
 0.993
AFM39395.1
Formate hydrogenlyase subunit 4; PFAM: NADH dehydrogenase.
 
 
 0.992
AFM39396.1
Hydrogenase 4 membrane component (E).
 
  
 0.982
AFM42505.1
PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains; NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus; TIGRFAM: proton-translocating NADH-quinone oxidoreductase, chain L.
 
 
0.931
AFM39394.1
Formate hydrogenlyase subunit 3/multisubunit Na+/H+ antiporter, MnhD subunit; PFAM: NADH-Ubiquinone/plastoquinone (complex I), various chains.
 
    
0.810
AFM39837.1
NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; 4Fe-4S binding domain; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain; TIGRFAM: NADH-quinone oxidoreductase, F subunit.
  
 
 0.690
AFM43311.1
NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit; PFAM: NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Respiratory-chain NADH dehydrogenase 24 Kd subunit; Respiratory-chain NADH dehydrogenase 51 Kd subunit; SLBB domain.
  
 
 0.690
nuoB
NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
 
 
 
 0.669
nuoD
NADH:ubiquinone oxidoreductase 49 kD subunit 7; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I 49 kDa subunit family.
 
 
   0.648
Your Current Organism:
Desulfosporosinus acidiphilus
NCBI taxonomy Id: 646529
Other names: D. acidiphilus SJ4, Desulfosporosinus acidiphilus DSM 22704, Desulfosporosinus acidiphilus SJ4, Desulfosporosinus acidiphilus str. SJ4, Desulfosporosinus acidiphilus strain SJ4, Desulfosporosinus sp. SJ4
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