Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AFM42108.1PFAM: Stage V sporulation protein S (SpoVS). (86 aa)    
Predicted Functional Partners:
AFM42109.1
TIGRFAM: metallophosphoesterase, MG_246/BB_0505 family.
  
    0.665
AFM42110.1
Hypothetical protein.
       0.464
AFM39150.1
Transcriptional regulator, AbrB family; PFAM: SpoVT / AbrB like domain; TIGRFAM: looped-hinge helix DNA binding domain, AbrB family.
  
   
 0.422
AFM42005.1
PFAM: SpoVR like protein.
  
   
 0.418
spoVG
Uncharacterized protein, involved in the regulation of septum location; Could be involved in septation.
      
 0.409
AFM42221.1
Response regulator receiver protein; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
  
 0.403
Your Current Organism:
Desulfosporosinus acidiphilus
NCBI taxonomy Id: 646529
Other names: D. acidiphilus SJ4, Desulfosporosinus acidiphilus DSM 22704, Desulfosporosinus acidiphilus SJ4, Desulfosporosinus acidiphilus str. SJ4, Desulfosporosinus acidiphilus strain SJ4, Desulfosporosinus sp. SJ4
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.