node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEH06051.1 | AEH07453.1 | Metok_0053 | Metok_1490 | KEGG: mif:Metin_1460 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | KEGG: mae:Maeo_0986 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.980 |
AEH06051.1 | purC | Metok_0053 | Metok_0799 | KEGG: mif:Metin_1460 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | PFAM: SAICAR synthetase; TIGRFAM: SAICAR synthetase; HAMAP: Phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: mae:Maeo_0468 phosphoribosylaminoimidazole-succinocarboxamide synthase. | 0.961 |
AEH06051.1 | purD | Metok_0053 | Metok_0590 | KEGG: mif:Metin_1460 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; TIGRFAM: Phosphoribosylglycinamide synthetase; HAMAP: Phosphoribosylglycinamide synthetase; KEGG: mae:Maeo_1322 phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.938 |
AEH06051.1 | purE | Metok_0053 | Metok_0092 | KEGG: mif:Metin_1460 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.863 |
AEH06051.1 | purL | Metok_0053 | Metok_0202 | KEGG: mif:Metin_1460 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.980 |
AEH06051.1 | purM | Metok_0053 | Metok_0360 | KEGG: mif:Metin_1460 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: mmq:MmarC5_0337 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein. | 0.950 |
AEH06051.1 | purQ | Metok_0053 | Metok_1462 | KEGG: mif:Metin_1460 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.961 |
AEH06051.1 | purS | Metok_0053 | Metok_0800 | KEGG: mif:Metin_1460 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] | 0.959 |
AEH06051.1 | purT | Metok_0053 | Metok_1025 | KEGG: mif:Metin_1460 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.905 |
AEH07453.1 | AEH06051.1 | Metok_1490 | Metok_0053 | KEGG: mae:Maeo_0986 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: mif:Metin_1460 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | 0.980 |
AEH07453.1 | purC | Metok_1490 | Metok_0799 | KEGG: mae:Maeo_0986 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | PFAM: SAICAR synthetase; TIGRFAM: SAICAR synthetase; HAMAP: Phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: mae:Maeo_0468 phosphoribosylaminoimidazole-succinocarboxamide synthase. | 0.999 |
AEH07453.1 | purD | Metok_1490 | Metok_0590 | KEGG: mae:Maeo_0986 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylamine--glycine ligase; PFAM: Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; TIGRFAM: Phosphoribosylglycinamide synthetase; HAMAP: Phosphoribosylglycinamide synthetase; KEGG: mae:Maeo_1322 phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.982 |
AEH07453.1 | purE | Metok_1490 | Metok_0092 | KEGG: mae:Maeo_0986 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.968 |
AEH07453.1 | purF | Metok_1490 | Metok_0245 | KEGG: mae:Maeo_0986 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. | 0.950 |
AEH07453.1 | purL | Metok_1490 | Metok_0202 | KEGG: mae:Maeo_0986 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase 2; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.973 |
AEH07453.1 | purM | Metok_1490 | Metok_0360 | KEGG: mae:Maeo_0986 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | TIGRFAM: Phosphoribosylformylglycinamidine cyclo-ligase; KEGG: mmq:MmarC5_0337 phosphoribosylaminoimidazole synthetase; PFAM: AIR synthase related protein, C-terminal; AIR synthase related protein. | 0.969 |
AEH07453.1 | purQ | Metok_1490 | Metok_1462 | KEGG: mae:Maeo_0986 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase 1; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.956 |
AEH07453.1 | purS | Metok_1490 | Metok_0800 | KEGG: mae:Maeo_0986 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] | 0.947 |
AEH07453.1 | purT | Metok_1490 | Metok_1025 | KEGG: mae:Maeo_0986 adenylosuccinate lyase; TIGRFAM: Adenylosuccinate lyase; PFAM: Fumarate lyase; Adenylosuccinate lyase, C-terminal; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. | 0.773 |
purC | AEH06051.1 | Metok_0799 | Metok_0053 | PFAM: SAICAR synthetase; TIGRFAM: SAICAR synthetase; HAMAP: Phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: mae:Maeo_0468 phosphoribosylaminoimidazole-succinocarboxamide synthase. | KEGG: mif:Metin_1460 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II. | 0.961 |