STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH06780.1KEGG: mae:Maeo_0120 cobaltochelatase; PFAM: CobN/magnesium chelatase. (1240 aa)    
Predicted Functional Partners:
cbiA
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source.
 
 
 0.955
AEH07135.1
KEGG: mae:Maeo_0109 cobaltochelatase subunit CobN; PFAM: CobN/magnesium chelatase.
  
  
 
0.911
AEH07215.1
UPF0284 protein; TIGRFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase, putative; HAMAP: UPF0284 protein; KEGG: mae:Maeo_0615 hypothetical protein; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase-like, core; Belongs to the UPF0284 family.
     
 0.891
AEH07136.1
Magnesium chelatase; PFAM: ATPase associated with various cellular activities, AAA-5; KEGG: mae:Maeo_0108 magnesium chelatase; SMART: ATPase, AAA+ type, core.
 
  
 0.870
AEH07137.1
SMART: von Willebrand factor, type A; KEGG: mfs:MFS40622_1250 magnesium chelatase.
 
  
 0.799
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
     
 0.763
AEH07037.1
Precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; KEGG: mja:MJ_1522 cobalt-precorrin-6Y C(5)-methyltransferase; TIGRFAM: Cobalamin (vitamin B12) biosynthesis CbiE, precorrin-6Y methyltransferase, core; PFAM: Tetrapyrrole methylase.
  
  
 0.641
AEH06682.1
PFAM: CobB/CobQ-like glutamine amidotransferase; KEGG: mae:Maeo_1143 cobyrinic acid a,c-diamide synthase.
  
 
 0.639
AEH06781.1
PFAM: 4Fe-4S ferredoxin, iron-sulphur binding, subgroup; KEGG: mae:Maeo_0121 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
 
   
 0.628
AEH06629.1
PFAM: Cobalamin (vitamin B12) biosynthesis CbiX; KEGG: mmz:MmarC7_1164 sirohydrochlorin cobaltochelatase.
     
 0.605
Your Current Organism:
Methanothermococcus okinawensis
NCBI taxonomy Id: 647113
Other names: M. okinawensis IH1, Methanothermococcus okinawensis DSM 14208, Methanothermococcus okinawensis IH1, Methanothermococcus okinawensis str. IH1, Methanothermococcus okinawensis strain IH1
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