STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH07243.1Protein of unknown function DUF105; PFAM: Adenosylcobinamide amidohydrolase, CbiZ; KEGG: mja:MJ_1613 hypothetical protein. (259 aa)    
Predicted Functional Partners:
AEH06878.1
PFAM: Xylose isomerase, TIM barrel domain; KEGG: mfs:MFS40622_0150 xylose isomerase domain protein TIM barrel.
 
     0.722
cobD
Cobalamin biosynthesis protein cbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
   
 0.538
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
       0.497
AEH07324.1
KEGG: mfe:Mefer_1225 PKD domain containing protein; PFAM: PKD; SMART: PKD.
 
     0.452
AEH06785.1
Iron-chelate-transporting ATPase; PFAM: ABC transporter-like; KEGG: mvu:Metvu_0757 ABC transporter releated protein; SMART: ATPase, AAA+ type, core.
 
     0.446
AEH07135.1
KEGG: mae:Maeo_0109 cobaltochelatase subunit CobN; PFAM: CobN/magnesium chelatase.
 
   
 0.434
AEH07321.1
PFAM: Protein of unknown function DUF2341; KEGG: mae:Maeo_0853 hypothetical protein.
  
     0.413
hisC
PFAM: Aminotransferase, class I/II; TIGRFAM: Histidinol-phosphate aminotransferase; HAMAP: Histidinol-phosphate aminotransferase; KEGG: mae:Maeo_0250 histidinol-phosphate aminotransferase.
     
 0.400
Your Current Organism:
Methanothermococcus okinawensis
NCBI taxonomy Id: 647113
Other names: M. okinawensis IH1, Methanothermococcus okinawensis DSM 14208, Methanothermococcus okinawensis IH1, Methanothermococcus okinawensis str. IH1, Methanothermococcus okinawensis strain IH1
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