STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH07336.1TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Ion transport 2; Regulator of K+ conductance, C-terminal; KEGG: mae:Maeo_0451 TrkA domain-containing protein. (335 aa)    
Predicted Functional Partners:
AEH07340.1
PFAM: Cation/H+ exchanger; KEGG: mae:Maeo_0743 sodium/hydrogen exchanger.
  
  
 0.906
AEH07430.1
TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; KEGG: mmq:MmarC5_1809 TrkA domain-containing protein.
  
  
0.799
AEH06344.1
KEGG: mae:Maeo_0815 DEAD/DEAH box helicase domain-containing protein; PFAM: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; DNA/RNA helicase, C-terminal; SMART: DEAD-like helicase, N-terminal; DNA/RNA helicase, C-terminal.
  
    0.629
secF
SecD/SecF/SecDF export membrane protein; Involved in protein export.
  
    0.504
AEH06212.1
Anion transporter; Manually curated; TIGRFAM: Sodium/sulphate symporter; KEGG: mae:Maeo_0884 anion transporter; PFAM: Sodium/sulphate symporter.
     
 0.488
aroE
Shikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
     
 0.471
hpt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
     
 0.466
secD
SecD/SecF/SecDF export membrane protein; Involved in protein export.
     
 0.459
AEH06459.1
KEGG: fpl:Ferp_1321 rhodanese domain protein; PFAM: Rhodanese-like; SMART: Rhodanese-like.
  
  
 0.439
argD
PFAM: Aminotransferase class-III; TIGRFAM: Acetylornithine/succinylornithine aminotransferase; HAMAP: Acetylornithine/succinyldiaminopimelate aminotransferase; KEGG: mae:Maeo_0640 acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
     
 0.420
Your Current Organism:
Methanothermococcus okinawensis
NCBI taxonomy Id: 647113
Other names: M. okinawensis IH1, Methanothermococcus okinawensis DSM 14208, Methanothermococcus okinawensis IH1, Methanothermococcus okinawensis str. IH1, Methanothermococcus okinawensis strain IH1
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