STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEH07340.1PFAM: Cation/H+ exchanger; KEGG: mae:Maeo_0743 sodium/hydrogen exchanger. (383 aa)    
Predicted Functional Partners:
AEH06681.1
TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Ion transport 2; Regulator of K+ conductance, C-terminal; KEGG: mae:Maeo_1142 TrkA domain-containing protein.
  
  
 0.906
AEH07336.1
TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Ion transport 2; Regulator of K+ conductance, C-terminal; KEGG: mae:Maeo_0451 TrkA domain-containing protein.
  
  
 0.906
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
     
 0.695
AEH07222.1
TIGRFAM: ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: mae:Maeo_0897 ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: ATPase, P-type, ATPase-associated region; ATPase, P-type cation-transporter, N-terminal; Haloacid dehalogenase-like hydrolase; ATPase, P-type cation-transporter, C-terminal.
 
 
 0.645
AEH06245.1
PFAM: Cation transporter; KEGG: mmp:MMP1430 cation transporter.
  
 
 0.562
AEH06051.1
KEGG: mif:Metin_1460 asparagine synthase (glutamine-hydrolyzing); TIGRFAM: Asparagine synthase, glutamine-hydrolyzing; PFAM: Asparagine synthase; Glutamine amidotransferase, class-II.
 
  
 0.557
AEH07430.1
TrkA-N domain protein; PFAM: Regulator of K+ conductance, N-terminal; Regulator of K+ conductance, C-terminal; KEGG: mmq:MmarC5_1809 TrkA domain-containing protein.
  
  
 0.545
AEH06486.1
TIGRFAM: ATPase, P-type, plasma-membrane proton-efflux; ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter; KEGG: mae:Maeo_0802 plasma-membrane proton-efflux P-type ATPase; PFAM: ATPase, P-type, ATPase-associated region; ATPase, P-type cation-transporter, N-terminal; Haloacid dehalogenase-like hydrolase.
 
 0.543
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
 
 0.494
AEH06583.1
PFAM: ADP-ribosylation/Crystallin J1; KEGG: mmz:MmarC7_1645 ADP-ribosylation/crystallin J1.
 
  
 0.483
Your Current Organism:
Methanothermococcus okinawensis
NCBI taxonomy Id: 647113
Other names: M. okinawensis IH1, Methanothermococcus okinawensis DSM 14208, Methanothermococcus okinawensis IH1, Methanothermococcus okinawensis str. IH1, Methanothermococcus okinawensis strain IH1
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