STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHP87075.1KEGG: mvn:Mevan_1407 signal transduction protein; PFAM: CBS domain containing protein; SMART: CBS domain containing protein. (321 aa)    
Predicted Functional Partners:
EHP87771.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mfe:Mefer_0246 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.840
EHP87077.1
TIGRFAM: methanogenesis marker protein 7; KEGG: methyl coenzyme M reductase II, operon protein C (MtrC).
  
    0.739
EHP87078.1
KEGG: hypothetical protein.
  
    0.725
EHP88555.1
KEGG: mfs:MFS40622_1238 small GTP-binding protein; TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related.
 
 0.711
guaAB
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
 
 0.671
EHP87081.1
PFAM: PfkB domain protein; KEGG: mfe:Mefer_1313 PfkB domain protein; Belongs to the carbohydrate kinase PfkB family.
  
 
 0.620
guaAA
GMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP.
  
 
 0.589
EHP87076.1
PFAM: Uncharacterised conserved protein UCP021940; KEGG: hypothetical protein.
       0.588
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 
 0.571
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
 
 
0.547
Your Current Organism:
Methanotorris formicicus
NCBI taxonomy Id: 647171
Other names: M. formicicus Mc-S-70, Methanotorris formicicus ATCC BAA-687, Methanotorris formicicus DSM 16983, Methanotorris formicicus Mc-S-70, Methanotorris formicicus stain Mc-S-70, Methanotorris formicicus str. Mc-S-70, Methanotorris sp. Mc-S-70
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.