STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EHP84386.1KEGG: mvu:Metvu_0739 putative signal transduction protein with CBS domains; PFAM: CBS domain containing protein; SMART: CBS domain containing protein. (153 aa)    
Predicted Functional Partners:
EHP84387.1
Beta-ribofuranosylaminobenzene 5'-phosphate synthase family; Catalyzes the condensation of 4-aminobenzoate (pABA) with 5- phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta- ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P).
  
    0.933
EHP87771.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mfe:Mefer_0246 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.840
EHP88555.1
KEGG: mfs:MFS40622_1238 small GTP-binding protein; TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein HSR1-related.
  
 0.665
guaAB
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
 0.623
guaAA
GMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP.
  
 
 0.589
EHP84385.1
KEGG: mmz:MmarC7_1280 TraB family protein; TIGRFAM: TraB family protein; PFAM: TraB determinant protein.
       0.587
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.514
hpt
Phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis. Belongs to the purine/pyrimidine phosphoribosyltransferase family. Archaeal HPRT subfamily.
  
 
 0.507
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.507
EHP85556.1
TIGRFAM: 3-hydroxy-3-methylglutaryl Coenzyme A reductase; KEGG: mfe:Mefer_1084 3-hydroxy-3-methylglutaryl coenzyme A reductase; PFAM: hydroxymethylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
  
 
 0.503
Your Current Organism:
Methanotorris formicicus
NCBI taxonomy Id: 647171
Other names: M. formicicus Mc-S-70, Methanotorris formicicus ATCC BAA-687, Methanotorris formicicus DSM 16983, Methanotorris formicicus Mc-S-70, Methanotorris formicicus stain Mc-S-70, Methanotorris formicicus str. Mc-S-70, Methanotorris sp. Mc-S-70
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