node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALC60_02499 | ALC60_05104 | A0A151XDN3 | A0A151X6S8 | NEDD8-activating enzyme E1 regulatory subunit. | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | 0.440 |
ALC60_02499 | ALC60_06708 | A0A151XDN3 | A0A151X2E0 | NEDD8-activating enzyme E1 regulatory subunit. | SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family. | 0.476 |
ALC60_02499 | ALC60_07263 | A0A151XDN3 | A0A151X0M9 | NEDD8-activating enzyme E1 regulatory subunit. | Ubiquitin-like modifier-activating enzyme 5. | 0.471 |
ALC60_02499 | ALC60_08924 | A0A151XDN3 | A0A151WVW5 | NEDD8-activating enzyme E1 regulatory subunit. | Ubiquitin-like modifier-activating enzyme 1; Belongs to the ubiquitin-activating E1 family. | 0.553 |
ALC60_02499 | ALC60_09627 | A0A151XDN3 | A0A151WTU5 | NEDD8-activating enzyme E1 regulatory subunit. | NEDD8-activating enzyme E1 catalytic subunit. | 0.999 |
ALC60_02499 | ALC60_10012 | A0A151XDN3 | A0A151WSS3 | NEDD8-activating enzyme E1 regulatory subunit. | Gephyrin. | 0.655 |
ALC60_02499 | ALC60_11551 | A0A151XDN3 | A0A151WP25 | NEDD8-activating enzyme E1 regulatory subunit. | Molybdenum cofactor biosynthesis protein 1. | 0.804 |
ALC60_02499 | ALC60_14828 | A0A151XDN3 | A0A151WE67 | NEDD8-activating enzyme E1 regulatory subunit. | Adenylyltransferase and sulfurtransferase MOCS3 homolog; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of the sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards U [...] | 0.487 |
ALC60_02499 | Mocs2 | A0A151XDN3 | A0A151WWL1 | NEDD8-activating enzyme E1 regulatory subunit. | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily. | 0.939 |
ALC60_05104 | ALC60_02499 | A0A151X6S8 | A0A151XDN3 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | NEDD8-activating enzyme E1 regulatory subunit. | 0.440 |
ALC60_05104 | ALC60_07263 | A0A151X6S8 | A0A151X0M9 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | Ubiquitin-like modifier-activating enzyme 5. | 0.779 |
ALC60_05104 | ALC60_08924 | A0A151X6S8 | A0A151WVW5 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | Ubiquitin-like modifier-activating enzyme 1; Belongs to the ubiquitin-activating E1 family. | 0.856 |
ALC60_05104 | ALC60_09627 | A0A151X6S8 | A0A151WTU5 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | NEDD8-activating enzyme E1 catalytic subunit. | 0.820 |
ALC60_05104 | ALC60_10012 | A0A151X6S8 | A0A151WSS3 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | Gephyrin. | 0.655 |
ALC60_05104 | ALC60_11551 | A0A151X6S8 | A0A151WP25 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | Molybdenum cofactor biosynthesis protein 1. | 0.804 |
ALC60_05104 | ALC60_14828 | A0A151X6S8 | A0A151WE67 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | Adenylyltransferase and sulfurtransferase MOCS3 homolog; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of the sulfur carrier URM1. Its N-terminus first activates URM1 as acyl-adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards U [...] | 0.527 |
ALC60_05104 | Mocs2 | A0A151X6S8 | A0A151WWL1 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for autophagy. | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily. | 0.939 |
ALC60_06708 | ALC60_02499 | A0A151X2E0 | A0A151XDN3 | SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family. | NEDD8-activating enzyme E1 regulatory subunit. | 0.476 |
ALC60_06708 | ALC60_08924 | A0A151X2E0 | A0A151WVW5 | SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family. | Ubiquitin-like modifier-activating enzyme 1; Belongs to the ubiquitin-activating E1 family. | 0.542 |
ALC60_06708 | ALC60_10012 | A0A151X2E0 | A0A151WSS3 | SUMO-activating enzyme subunit; Belongs to the ubiquitin-activating E1 family. | Gephyrin. | 0.655 |