STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALC60_07714Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (952 aa)    
Predicted Functional Partners:
ALC60_04790
Fanconi anemia group D2 protein.
    
 0.986
ALC60_08687
DNA mismatch repair protein Mlh1.
    
 0.984
ALC60_06864
Mismatch repair endonuclease PMS2.
    
 0.969
ALC60_10949
Fanconi anemia group I protein.
    
 0.905
ALC60_10697
DDE_Tnp_IS1595 domain-containing protein.
    
 0.866
ALC60_10644
Uncharacterized protein.
    
 0.866
ALC60_10766
Crossover junction endonuclease MUS81.
    
 0.859
ALC60_12492
DNA repair endonuclease XPF.
    
 0.858
ALC60_11759
Structure-specific endonuclease subunit SLX1 homolog; Catalytic subunit of a heterodimeric structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA; Belongs to the SLX1 family.
   
 
 0.838
ALC60_03716
DNA excision repair protein ERCC-1.
     
 0.824
Your Current Organism:
Trachymyrmex zeteki
NCBI taxonomy Id: 64791
Other names: T. zeteki
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