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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rvan_0027PFAM: NAD-dependent epimerase/dehydratase; KEGG: aca:ACP_0749 NAD dependent epimerase/dehydratase family protein. (336 aa)    
Predicted Functional Partners:
Rvan_2201
TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: azl:AZL_f01870 mannose-1-phosphate guanylyltransferase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.924
Rvan_2462
TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; KEGG: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Belongs to the mannose-6-phosphate isomerase type 2 family.
  
 
 0.924
Rvan_2278
TIGRFAM: nucleotide sugar dehydrogenase; KEGG: mmr:Mmar10_2489 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase.
 
 0.886
Rvan_0843
Glucose-1-phosphate cytidylyltransferase; KEGG: bov:BOV_A0382 nucleotidyltransferase family protein.
  
 0.873
gmd
GDP-mannose 4,6-dehydratase; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose.
  
 0.873
Rvan_2951
Manually curated; TIGRFAM: UDP-glucose 4-epimerase; KEGG: mei:Msip34_1820 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family.
 
 0.857
Rvan_3089
Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
  
 
 0.839
glmU
UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
  
 
 0.821
Rvan_1313
TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; KEGG: bid:Bind_0435 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase.
    
 0.821
rpsS
Ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.
   
  0.724
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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