Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rvan_0178PFAM: peptidase M50; CBS domain containing protein; KEGG: sat:SYN_00323 M50 family membrane endopeptidase; Belongs to the peptidase M50B family. (387 aa)    
Predicted Functional Partners:
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
  
 
 0.812
rpsO
Ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
  
   0.778
Rvan_0614
TIGRFAM: pyruvate kinase; KEGG: nha:Nham_1218 pyruvate kinase; PFAM: Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
  
 
 0.769
rpsB
Ribosomal protein S2; KEGG: msl:Msil_1694 30S ribosomal protein S2; TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
   0.765
rplM
Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
  
   0.758
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
  
 
 0.748
Rvan_0884
Rhodanese domain protein; KEGG: mag:amb2171 rhodanese-related sulfurtransferase; PFAM: Rhodanese domain protein; SMART: Rhodanese domain protein.
 
 
   0.747
Rvan_1843
KEGG: rpt:Rpal_0733 ABC transporter related; PFAM: ABC transporter related; inner-membrane translocator; SMART: AAA ATPase; Belongs to the binding-protein-dependent transport system permease family.
  
    0.742
Rvan_2960
KEGG: met:M446_1796 ABC transporter related; PFAM: ABC transporter related; inner-membrane translocator; SMART: AAA ATPase; Belongs to the binding-protein-dependent transport system permease family.
  
    0.742
rpsD
Ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
 
 0.741
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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