| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rvan_0178 | Rvan_0179 | Rvan_0178 | Rvan_0179 | PFAM: peptidase M50; CBS domain containing protein; KEGG: sat:SYN_00323 M50 family membrane endopeptidase; Belongs to the peptidase M50B family. | PFAM: isochorismatase hydrolase; KEGG: met:M446_0481 isochorismatase hydrolase. | 0.462 |
| Rvan_0178 | Rvan_0737 | Rvan_0178 | Rvan_0737 | PFAM: peptidase M50; CBS domain containing protein; KEGG: sat:SYN_00323 M50 family membrane endopeptidase; Belongs to the peptidase M50B family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.487 |
| Rvan_0178 | guaA | Rvan_0178 | Rvan_1695 | PFAM: peptidase M50; CBS domain containing protein; KEGG: sat:SYN_00323 M50 family membrane endopeptidase; Belongs to the peptidase M50B family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.812 |
| Rvan_0179 | Rvan_0178 | Rvan_0179 | Rvan_0178 | PFAM: isochorismatase hydrolase; KEGG: met:M446_0481 isochorismatase hydrolase. | PFAM: peptidase M50; CBS domain containing protein; KEGG: sat:SYN_00323 M50 family membrane endopeptidase; Belongs to the peptidase M50B family. | 0.462 |
| Rvan_0179 | Rvan_0737 | Rvan_0179 | Rvan_0737 | PFAM: isochorismatase hydrolase; KEGG: met:M446_0481 isochorismatase hydrolase. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.410 |
| Rvan_0179 | Rvan_1173 | Rvan_0179 | Rvan_1173 | PFAM: isochorismatase hydrolase; KEGG: met:M446_0481 isochorismatase hydrolase. | PFAM: nitroreductase; KEGG: bur:Bcep18194_B1060 hypothetical protein. | 0.424 |
| Rvan_0179 | Rvan_1649 | Rvan_0179 | Rvan_1649 | PFAM: isochorismatase hydrolase; KEGG: met:M446_0481 isochorismatase hydrolase. | PFAM: N-formylglutamate amidohydrolase; KEGG: N-formylglutamate amidohydrolase. | 0.425 |
| Rvan_0179 | Rvan_1664 | Rvan_0179 | Rvan_1664 | PFAM: isochorismatase hydrolase; KEGG: met:M446_0481 isochorismatase hydrolase. | PFAM: alpha/beta hydrolase fold; KEGG: mxa:MXAN_6875 alpha/beta fold family hydrolase. | 0.555 |
| Rvan_0179 | Rvan_1936 | Rvan_0179 | Rvan_1936 | PFAM: isochorismatase hydrolase; KEGG: met:M446_0481 isochorismatase hydrolase. | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: fumarate reductase/succinate dehydrogenase flavoprotein domain protein. | 0.455 |
| Rvan_0179 | gpsA | Rvan_0179 | Rvan_2215 | PFAM: isochorismatase hydrolase; KEGG: met:M446_0481 isochorismatase hydrolase. | PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; Ketopantoate reductase ApbA/PanE domain protein; KEGG: pla:Plav_1343 glycerol-3-phosphate dehydrogenase (NAD(P)(+)). | 0.519 |
| Rvan_0179 | guaA | Rvan_0179 | Rvan_1695 | PFAM: isochorismatase hydrolase; KEGG: met:M446_0481 isochorismatase hydrolase. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.450 |
| Rvan_0179 | nadE | Rvan_0179 | Rvan_2752 | PFAM: isochorismatase hydrolase; KEGG: met:M446_0481 isochorismatase hydrolase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.592 |
| Rvan_0179 | nnrD | Rvan_0179 | Rvan_0543 | PFAM: isochorismatase hydrolase; KEGG: met:M446_0481 isochorismatase hydrolase. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...] | 0.576 |
| Rvan_0737 | Rvan_0178 | Rvan_0737 | Rvan_0178 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | PFAM: peptidase M50; CBS domain containing protein; KEGG: sat:SYN_00323 M50 family membrane endopeptidase; Belongs to the peptidase M50B family. | 0.487 |
| Rvan_0737 | Rvan_0179 | Rvan_0737 | Rvan_0179 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | PFAM: isochorismatase hydrolase; KEGG: met:M446_0481 isochorismatase hydrolase. | 0.410 |
| Rvan_0737 | Rvan_1936 | Rvan_0737 | Rvan_1936 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: fumarate reductase/succinate dehydrogenase flavoprotein domain protein. | 0.411 |
| Rvan_0737 | guaA | Rvan_0737 | Rvan_1695 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.633 |
| Rvan_0737 | nadE | Rvan_0737 | Rvan_2752 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.664 |
| Rvan_1173 | Rvan_0179 | Rvan_1173 | Rvan_0179 | PFAM: nitroreductase; KEGG: bur:Bcep18194_B1060 hypothetical protein. | PFAM: isochorismatase hydrolase; KEGG: met:M446_0481 isochorismatase hydrolase. | 0.424 |
| Rvan_1649 | Rvan_0179 | Rvan_1649 | Rvan_0179 | PFAM: N-formylglutamate amidohydrolase; KEGG: N-formylglutamate amidohydrolase. | PFAM: isochorismatase hydrolase; KEGG: met:M446_0481 isochorismatase hydrolase. | 0.425 |