Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rvan_0227PFAM: dihydroneopterin aldolase; KEGG: bid:Bind_3577 dihydroneopterin aldolase. (140 aa)    
Predicted Functional Partners:
Rvan_1203
TIGRFAM: dihydropteroate synthase; KEGG: rce:RC1_1795 dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS.
 
 
 0.995
Rvan_2205
KEGG: pla:Plav_2866 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK.
  
 
 0.994
folE
TIGRFAM: GTP cyclohydrolase I; KEGG: hba:Hbal_2379 GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I/Nitrile oxidoreductase.
  
  
 0.946
Rvan_1563
KEGG: hne:HNE_3483 alkaline phosphatase; PFAM: Alkaline phosphatase; SMART: Alkaline phosphatase; Belongs to the alkaline phosphatase family.
     
 0.904
Rvan_1685
Chorismate binding-like protein; KEGG: ajs:Ajs_3496 para-aminobenzoate synthase, subunit I; manually curated; PFAM: Chorismate binding-like; aminotransferase class IV.
  
  
 0.701
Rvan_0904
KEGG: met:M446_0475 FolC bifunctional protein; TIGRFAM: FolC bifunctional protein; PFAM: Mur ligase middle domain protein; cytoplasmic peptidoglycan synthetase domain protein; Belongs to the folylpolyglutamate synthase family.
  
  
 0.700
Rvan_0737
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.691
ispDF
2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
  
  
 0.670
Rvan_0241
PFAM: protein of unknown function DUF1045; KEGG: rsq:Rsph17025_0908 hypothetical protein.
 
  
 0.617
Rvan_0226
Hypothetical protein; KEGG: type III restriction-modification system, restriction endonucleasesubunit.
       0.590
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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