Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rvan_0244Integral membrane sensor signal transduction histidine kinase; KEGG: azc:AZC_4692 histidine kinase A; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein. (442 aa)    
Predicted Functional Partners:
Rvan_0245
KEGG: azc:AZC_4693 transcriptional regulator; PFAM: response regulator receiver; SMART: response regulator receiver.
 0.996
Rvan_1333
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
    
 0.863
Rvan_0549
KEGG: met:M446_2639 hypothetical protein.
  
     0.740
Rvan_2392
Manually curated; PFAM: ATP-binding region ATPase domain protein; KEGG: pla:Plav_0305 integral membrane sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein.
  
     0.708
Rvan_0243
PFAM: electron transport protein SCO1/SenC; KEGG: bja:blr1131 putative cytochrome c oxidase assembly factor transmembrane protein.
     
 0.666
Rvan_1915
PFAM: protein of unknown function DUF1153; KEGG: azc:AZC_1033 hypothetical protein.
  
    0.666
Rvan_2313
KEGG: azc:AZC_4463 hypothetical protein.
  
     0.585
Rvan_3673
PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; KEGG: bra:BRADO1833 hypothetical protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS domain containing protein; response regulator receiver.
 
 
 
 0.576
Rvan_2917
Two component transcriptional regulator, winged helix family; KEGG: mlo:mlr4237 two-component response regulator; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver.
  
 
 0.566
Rvan_3254
KEGG: mes:Meso_0097 2'-deoxycytidine 5'-triphosphate deaminase.
  
     0.559
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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