STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rvan_0263KEGG: mrd:Mrad2831_4673 putative DNA helicase. (1994 aa)    
Predicted Functional Partners:
Rvan_1461
KEGG: pol:Bpro_1557 hypothetical protein.
  
    0.752
Rvan_3141
PFAM: EcoEI R domain protein; type III restriction protein res subunit; protein of unknown function DUF450; KEGG: hsdR3; type I restriction-modification system RcaSBIV subunit R; SMART: DEAD-like helicase.
  
    0.517
Rvan_1419
PFAM: N-6 DNA methylase; KEGG: rme:Rmet_6243 hypothetical protein.
  
  
 0.480
Rvan_1907
PFAM: N-6 DNA methylase; KEGG: sme:SMc02296 putative modification enzyme transmembrane protein.
  
  
 0.480
Rvan_2836
KEGG: bid:Bind_2672 N-6 DNA methylase; TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase.
  
  
 0.480
Rvan_3143
PFAM: N-6 DNA methylase; KEGG: hsdM3; type I restriction-modification system RcaSBIV subunit M.
  
  
 0.480
nnrD
Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow t [...]
  
    0.438
Rvan_0421
PFAM: acyltransferase 3; KEGG: smd:Smed_1772 acyltransferase 3.
  
    0.409
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
Server load: medium (56%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.