Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Rvan_0318PFAM: Collagen triple helix repeat-containing protein; KEGG: mlo:mlr0587 hypothetical protein. (834 aa)    
Predicted Functional Partners:
Rvan_0302
PFAM: BolA family protein; KEGG: ptr:457263 bolA homolog 1 (E. coli); Belongs to the BolA/IbaG family.
  
     0.704
Rvan_2642
PFAM: thiamine pyrophosphate TPP-binding domain-containing protein; thiamine pyrophosphate central domain-containing protein; KEGG: rfr:Rfer_2478 thiamine pyrophosphate enzyme-like TPP binding protein; Belongs to the TPP enzyme family.
  
     0.662
Rvan_0527
KEGG: nha:Nham_0078 hypothetical protein.
  
     0.627
Rvan_2494
PFAM: TROVE domain-containing protein; KEGG: mrd:Mrad2831_1806 TROVE domain-containing protein.
  
     0.617
Rvan_1555
KEGG: mno:Mnod_3763 peptidase M10A and M12B matrixin and adamalysin; PFAM: peptidase M10A and M12B matrixin and adamalysin; SMART: peptidase metallopeptidase.
  
     0.607
Rvan_1630
Oxygen-independent coproporphyrinogen III oxidase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
     0.603
Rvan_0317
KEGG: acr:Acry_1898 ABC transporter related; PFAM: ABC transporter related; ABC transporter transmembrane region; peptidase C39 bacteriocin processing; SMART: AAA ATPase.
  
    0.559
Rvan_1230
KEGG: TonB-dependent receptor plug domain-containing protein; manually curated; PFAM: TonB-dependent receptor; TonB-dependent receptor plug; Secretin/TonB short domain.
    
 
 0.558
Rvan_1724
PFAM: TonB-dependent receptor plug; TonB-dependent receptor; KEGG: rpt:Rpal_2027 TonB-dependent receptor.
    
 
 0.558
Rvan_2516
KEGG: rce:RC1_3856 TonB-dependent hemoglobin; TIGRFAM: TonB-dependent heme/hemoglobin receptor family protein; TonB-dependent hemoglobin/transferrin/lactoferrin family receptor; PFAM: TonB-dependent receptor plug; TonB-dependent receptor.
    
 
 0.558
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
Server load: low (18%) [HD]