Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rvan_0494PFAM: cobalamin synthesis protein P47K; KEGG: avn:Avin_00470 nickel incorporation protein. (234 aa)    
Predicted Functional Partners:
Rvan_0495
KEGG: avn:Avin_00480 ABC transporter, ATP binding component; PFAM: ABC transporter related; SMART: AAA ATPase.
    0.985
Rvan_0493
KEGG: avn:Avin_00460 hypothetical protein.
 
     0.948
Rvan_0502
KEGG: rpa:RPA1391 ABC transporter ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.
    0.929
Rvan_0289
PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; KEGG: xau:Xaut_0170 NADH-ubiquinone oxidoreductase chain 49kDa.
   
 
 0.912
Rvan_0492
PFAM: periplasmic binding protein; KEGG: avn:Avin_00450 ABC transporter, periplasmic binding protein.
 
     0.843
Rvan_0504
KEGG: rpa:RPA1389 hypothetical protein.
 
     0.781
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
 
 0.685
Rvan_0978
KEGG: slt:Slit_2421 hydrogenase expression/formation protein HypD; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; Belongs to the HypD family.
  
  
 0.653
Rvan_0496
PFAM: periplasmic binding protein; KEGG: avn:Avin_00450 ABC transporter, periplasmic binding protein.
 
     0.642
Rvan_0969
Hydrogenase assembly chaperone hypC/hupF; KEGG: bbt:BBta_2000 hydrogenase expression/formation; TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC).
  
  
 0.577
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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