STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rvan_0685KEGG: rpb:RPB_3420 coenzyme PQQ synthesis D. (99 aa)    
Predicted Functional Partners:
pqqE
Coenzyme PQQ biosynthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
 
  
 0.964
pqqC
Coenzyme PQQ biosynthesis protein C; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.
 
  
 0.962
pqqB
Coenzyme PQQ biosynthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.
 
  
 0.863
Rvan_0683
KEGG: bra:BRADO5461 hypothetical protein.
  
     0.695
Rvan_1822
TIGRFAM: PQQ-dependent dehydrogenase, methanol/ethanol family; PFAM: PQQ-dependent enzyme-like; Pyrrolo-quinoline quinone repeat-containing protein; KEGG: azo:azo2972 ExaA2 protein; SMART: Pyrrolo-quinoline quinone beta-propeller repeat.
 
  
 0.568
Rvan_0688
PFAM: Squalene/phytoene synthase; KEGG: mrd:Mrad2831_2279 squalene/phytoene synthase.
       0.476
Rvan_0687
PFAM: ATP12 ATPase; KEGG: sjp:SJA_C1-15430 ATP synthase mitochondrial F1 complex assembly factor 2.
       0.468
secF
Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
       0.468
Rvan_0689
PFAM: protein of unknown function DUF498; KEGG: tgr:Tgr7_1437 hypothetical protein.
       0.465
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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