Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pqqCCoenzyme PQQ biosynthesis protein C; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. (261 aa)    
Predicted Functional Partners:
pqqB
Coenzyme PQQ biosynthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.
  
 0.993
pqqE
Coenzyme PQQ biosynthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
 
  
 0.984
Rvan_0685
KEGG: rpb:RPB_3420 coenzyme PQQ synthesis D.
 
  
 0.969
Rvan_1822
TIGRFAM: PQQ-dependent dehydrogenase, methanol/ethanol family; PFAM: PQQ-dependent enzyme-like; Pyrrolo-quinoline quinone repeat-containing protein; KEGG: azo:azo2972 ExaA2 protein; SMART: Pyrrolo-quinoline quinone beta-propeller repeat.
 
  
 0.824
Rvan_1825
PFAM: cytochrome c class I; KEGG: azl:AZL_a09940 cytochrome c550.
 
  
 0.676
Rvan_2602
KEGG: rrs:RoseRS_2053 peptidase S9 prolyl oligopeptidase.
  
    0.603
Rvan_0683
KEGG: bra:BRADO5461 hypothetical protein.
  
     0.596
Rvan_3015
KEGG: oca:OCAR_6668 hopanoid biosynthesis associated radical SAM protein HpnH; TIGRFAM: hopanoid biosynthesis associated radical SAM protein HpnH; PFAM: Radical SAM domain protein.
 
  
 0.538
Rvan_0688
PFAM: Squalene/phytoene synthase; KEGG: mrd:Mrad2831_2279 squalene/phytoene synthase.
     
 0.492
Rvan_1644
KEGG: xau:Xaut_0477 glutamate synthase (ferredoxin); PFAM: glutamine amidotransferase class-II; glutamate synthase; ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein.
      
 0.484
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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