node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rvan_0362 | pheT | Rvan_0362 | Rvan_1040 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | KEGG: pla:Plav_0221 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. | 0.566 |
Rvan_0362 | secA | Rvan_0362 | Rvan_0127 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | 0.997 |
Rvan_0362 | secD | Rvan_0362 | Rvan_0691 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.955 |
Rvan_0362 | secE | Rvan_0362 | Rvan_2656 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.999 |
Rvan_0362 | secF | Rvan_0362 | Rvan_0690 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.773 |
Rvan_0362 | secY | Rvan_0362 | Rvan_3000 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.997 |
Rvan_0362 | yajC | Rvan_0362 | Rvan_0692 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.950 |
Rvan_0362 | yidC | Rvan_0362 | Rvan_0479 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Membrane protein insertase, YidC/Oxa1 family; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.987 |
Rvan_3247 | alaS | Rvan_3247 | Rvan_3023 | TIGRFAM: signal peptidase I; KEGG: xau:Xaut_3880 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.515 |
Rvan_3247 | pheT | Rvan_3247 | Rvan_1040 | TIGRFAM: signal peptidase I; KEGG: xau:Xaut_3880 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | KEGG: pla:Plav_0221 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. | 0.480 |
Rvan_3247 | secA | Rvan_3247 | Rvan_0127 | TIGRFAM: signal peptidase I; KEGG: xau:Xaut_3880 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | 0.560 |
Rvan_3247 | secD | Rvan_3247 | Rvan_0691 | TIGRFAM: signal peptidase I; KEGG: xau:Xaut_3880 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.783 |
Rvan_3247 | secE | Rvan_3247 | Rvan_2656 | TIGRFAM: signal peptidase I; KEGG: xau:Xaut_3880 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.461 |
Rvan_3247 | secF | Rvan_3247 | Rvan_0690 | TIGRFAM: signal peptidase I; KEGG: xau:Xaut_3880 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.743 |
Rvan_3247 | secY | Rvan_3247 | Rvan_3000 | TIGRFAM: signal peptidase I; KEGG: xau:Xaut_3880 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.685 |
Rvan_3247 | yajC | Rvan_3247 | Rvan_0692 | TIGRFAM: signal peptidase I; KEGG: xau:Xaut_3880 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.486 |
Rvan_3247 | yidC | Rvan_3247 | Rvan_0479 | TIGRFAM: signal peptidase I; KEGG: xau:Xaut_3880 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | Membrane protein insertase, YidC/Oxa1 family; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.817 |
alaS | Rvan_3247 | Rvan_3023 | Rvan_3247 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | TIGRFAM: signal peptidase I; KEGG: xau:Xaut_3880 signal peptidase I; PFAM: Peptidase S24/S26A/S26B, conserved region; Belongs to the peptidase S26 family. | 0.515 |
alaS | pheT | Rvan_3023 | Rvan_1040 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | KEGG: pla:Plav_0221 phenylalanyl-tRNA synthetase, beta subunit; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. | 0.919 |
alaS | secA | Rvan_3023 | Rvan_0127 | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. | 0.424 |