Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rvan_0703PFAM: pyruvate carboxyltransferase; KEGG: azc:AZC_1996 hydroxymethylglutaryl-CoA lyase. (292 aa)    
Predicted Functional Partners:
Rvan_3071
PFAM: Enoyl-CoA hydratase/isomerase; KEGG: rfr:Rfer_2816 enoyl-CoA hydratase/isomerase.
 
 
 0.991
Rvan_0701
KEGG: nha:Nham_2125 propionyl-CoA carboxylase; PFAM: carboxyl transferase.
 
 0.949
Rvan_0111
acetoacetyl-CoA synthase; KEGG: bmr:BMI_I21 acetyl-coenzyme A synthetase; TIGRFAM: acetoacetyl-CoA synthase; PFAM: AMP-dependent synthetase and ligase.
 
 0.947
Rvan_0702
PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; biotin/lipoyl attachment domain-containing protein; KEGG: rpt:Rpal_2809 carbamoyl-phosphate synthase L chain ATP-binding.
 
  
 0.931
Rvan_0023
TIGRFAM: acetyl-CoA acetyltransferase; KEGG: azl:AZL_023130 acetyl-CoA C-acetyltransferase; PFAM: Thiolase-like; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.927
Rvan_0557
TIGRFAM: acetyl-CoA acetyltransferase; KEGG: rce:RC1_1744 3-ketoacyl-CoA thiolase; PFAM: Thiolase-like; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.927
Rvan_0850
TIGRFAM: acetyl-CoA acetyltransferase; KEGG: maq:Maqu_2016 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.927
Rvan_3408
TIGRFAM: acetyl-CoA acetyltransferase; KEGG: tmz:Tmz1t_0732 acetyl-CoA acetyltransferase; PFAM: Thiolase-like; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.927
Rvan_0168
PFAM: short-chain dehydrogenase/reductase SDR; KEGG: rle:pRL90175 3-hydroxybutyrate dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
 
 0.918
sucC
succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.827
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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