Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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Rvan_0762TIGRFAM: heavy metal translocating P-type ATPase; copper-translocating P-type ATPase; ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: E1-E2 ATPase-associated domain protein; YHS domain-containing protein; Haloacid dehalogenase domain protein hydrolase; KEGG: pzu:PHZ_c1055 heavy-metal transporting P-type ATPase; SMART: TRASH domain-containing protein. (782 aa)    
Predicted Functional Partners:
cobB
PFAM: Silent information regulator protein Sir2; KEGG: rce:RC1_2898 NAD-dependent deacetylase; Belongs to the sirtuin family. Class III subfamily.
  
    0.559
Rvan_2061
KEGG: bbt:BBta_3643 cation efflux system protein; TIGRFAM: heavy metal efflux pump, CzcA family; PFAM: acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
   
 0.559
Rvan_0737
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
    0.430
Rvan_0764
PFAM: Methyltransferase type 11; KEGG: cak:Caul_2158 methyltransferase type 11.
       0.414
Rvan_0680
PFAM: protein of unknown function DUF156; KEGG: protein of unknown function DUF156.
 
  
 0.411
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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