| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Rvan_0399 | Rvan_3525 | Rvan_0399 | Rvan_3525 | KEGG: tkm:TK90_2543 nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: met:M446_3311 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.995 |
| Rvan_0399 | glmU | Rvan_0399 | Rvan_0790 | KEGG: tkm:TK90_2543 nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.923 |
| Rvan_1313 | Rvan_2278 | Rvan_1313 | Rvan_2278 | TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; KEGG: bid:Bind_0435 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase. | TIGRFAM: nucleotide sugar dehydrogenase; KEGG: mmr:Mmar10_2489 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. | 0.982 |
| Rvan_1313 | Rvan_2951 | Rvan_1313 | Rvan_2951 | TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; KEGG: bid:Bind_0435 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase. | Manually curated; TIGRFAM: UDP-glucose 4-epimerase; KEGG: mei:Msip34_1820 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | 0.972 |
| Rvan_1313 | Rvan_3525 | Rvan_1313 | Rvan_3525 | TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; KEGG: bid:Bind_0435 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase. | TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: met:M446_3311 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.884 |
| Rvan_1313 | glmS | Rvan_1313 | Rvan_0792 | TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; KEGG: bid:Bind_0435 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase. | Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.455 |
| Rvan_1313 | glmU | Rvan_1313 | Rvan_0790 | TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; KEGG: bid:Bind_0435 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.922 |
| Rvan_1313 | murA | Rvan_1313 | Rvan_0550 | TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; KEGG: bid:Bind_0435 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.870 |
| Rvan_1313 | prs | Rvan_1313 | Rvan_1714 | TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; KEGG: bid:Bind_0435 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.428 |
| Rvan_2278 | Rvan_1313 | Rvan_2278 | Rvan_1313 | TIGRFAM: nucleotide sugar dehydrogenase; KEGG: mmr:Mmar10_2489 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. | TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; KEGG: bid:Bind_0435 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase. | 0.982 |
| Rvan_2278 | Rvan_2951 | Rvan_2278 | Rvan_2951 | TIGRFAM: nucleotide sugar dehydrogenase; KEGG: mmr:Mmar10_2489 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. | Manually curated; TIGRFAM: UDP-glucose 4-epimerase; KEGG: mei:Msip34_1820 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | 0.943 |
| Rvan_2278 | Rvan_3525 | Rvan_2278 | Rvan_3525 | TIGRFAM: nucleotide sugar dehydrogenase; KEGG: mmr:Mmar10_2489 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. | TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: met:M446_3311 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.686 |
| Rvan_2278 | glmU | Rvan_2278 | Rvan_0790 | TIGRFAM: nucleotide sugar dehydrogenase; KEGG: mmr:Mmar10_2489 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.873 |
| Rvan_2951 | Rvan_1313 | Rvan_2951 | Rvan_1313 | Manually curated; TIGRFAM: UDP-glucose 4-epimerase; KEGG: mei:Msip34_1820 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | TIGRFAM: UTP-glucose-1-phosphate uridylyltransferase; KEGG: bid:Bind_0435 UTP-glucose-1-phosphate uridylyltransferase; PFAM: Nucleotidyl transferase. | 0.972 |
| Rvan_2951 | Rvan_2278 | Rvan_2951 | Rvan_2278 | Manually curated; TIGRFAM: UDP-glucose 4-epimerase; KEGG: mei:Msip34_1820 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | TIGRFAM: nucleotide sugar dehydrogenase; KEGG: mmr:Mmar10_2489 UDP-glucose 6-dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase. | 0.943 |
| Rvan_2951 | glmS | Rvan_2951 | Rvan_0792 | Manually curated; TIGRFAM: UDP-glucose 4-epimerase; KEGG: mei:Msip34_1820 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.497 |
| Rvan_2951 | glmU | Rvan_2951 | Rvan_0790 | Manually curated; TIGRFAM: UDP-glucose 4-epimerase; KEGG: mei:Msip34_1820 UDP-glucose 4-epimerase; PFAM: NAD-dependent epimerase/dehydratase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.884 |
| Rvan_3095 | glmU | Rvan_3095 | Rvan_0790 | PFAM: Uncharacterised protein family UPF0079, ATPase; aminoglycoside phosphotransferase; KEGG: msl:Msil_0666 protein of unknown function UPF0079. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.941 |
| Rvan_3095 | murA | Rvan_3095 | Rvan_0550 | PFAM: Uncharacterised protein family UPF0079, ATPase; aminoglycoside phosphotransferase; KEGG: msl:Msil_0666 protein of unknown function UPF0079. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.489 |
| Rvan_3525 | Rvan_0399 | Rvan_3525 | Rvan_0399 | TIGRFAM: UDP-N-acetylglucosamine 2-epimerase; KEGG: met:M446_3311 UDP-N-acetylglucosamine 2-epimerase; PFAM: UDP-N-acetylglucosamine 2-epimerase; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | KEGG: tkm:TK90_2543 nucleotide sugar dehydrogenase; TIGRFAM: nucleotide sugar dehydrogenase; PFAM: UDP-glucose/GDP-mannose dehydrogenase; UDP-glucose/GDP-mannose dehydrogenase dimerisation; UDP-glucose/GDP-mannose dehydrogenase; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.995 |