STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pepALeucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (515 aa)    
Predicted Functional Partners:
Rvan_0954
KEGG: aminopeptidase N; TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase.
  
 0.925
gshB
TIGRFAM: glutathione synthetase; KEGG: mlo:mll4735 glutathione synthetase; PFAM: glutathione synthetase ATP-binding; glutathione synthetase domain protein; Belongs to the prokaryotic GSH synthase family.
   
 
 0.925
Rvan_2611
PFAM: peptidase M17 leucyl aminopeptidase domain protein; KEGG: bbt:BBta_7039 leucine aminopeptidase; Belongs to the peptidase M17 family.
  
  
 
0.921
Rvan_2422
TIGRFAM: gamma-glutamyltransferase; KEGG: pde:Pden_0660 gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase.
   
 
 0.913
Rvan_3050
ChaC family protein; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family.
     
 0.901
Rvan_1731
Glutamate/cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily.
     
  0.900
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.827
Rvan_1278
PFAM: aminotransferase class I and II; KEGG: pla:Plav_2300 aspartate aminotransferase.
   
  0.821
Rvan_2359
KEGG: rhi:NGR_c36850 cysteine synthase A; TIGRFAM: cysteine synthase A; cysteine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit.
    
 0.821
Rvan_2944
PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: pla:Plav_2990 pyridoxal-5'-phosphate-dependent protein beta subunit.
    
 0.821
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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