Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rvan_0902Manually curated; TIGRFAM: lytic murein transglycosylase; KEGG: xau:Xaut_3846 lytic murein transglycosylase; PFAM: Peptidoglycan-binding domain 1 protein. (415 aa)    
Predicted Functional Partners:
Rvan_2122
KEGG: pla:Plav_2415 peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain.
   
 
 0.524
Rvan_1350
KEGG: azc:AZC_0926 hypothetical protein.
  
     0.463
ftsE
Cell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division.
     
 0.458
Rvan_1703
N-acetylmuramyl-L-alanine amidase, negative regulator of AmpC, AmpD; KEGG: azc:AZC_4549 N-acetylmuramoyl-L-alanine amidase; PFAM: N-acetylmuramoyl-L-alanine amidase family 2; Peptidoglycan-binding domain 1 protein; SMART: N-acetylmuramoyl-L-alanine amidase family 2.
     
 0.444
Rvan_0903
TIGRFAM: carboxyl-terminal protease; PFAM: peptidase S41; PDZ/DHR/GLGF domain protein; KEGG: azc:AZC_4133 peptidase S41A protein; SMART: peptidase S41; PDZ/DHR/GLGF domain protein; Belongs to the peptidase S41A family.
       0.436
murE
UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
      
 0.428
Rvan_2263
PFAM: Antibiotic biosynthesis monooxygenase; KEGG: xau:Xaut_1109 antibiotic biosynthesis monooxygenase.
  
     0.427
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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