node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rvan_0665 | Rvan_0944 | Rvan_0665 | Rvan_0944 | PFAM: IstB domain protein ATP-binding protein; KEGG: bja:bll4999 transposase. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.828 |
Rvan_0944 | Rvan_0665 | Rvan_0944 | Rvan_0665 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | PFAM: IstB domain protein ATP-binding protein; KEGG: bja:bll4999 transposase. | 0.828 |
Rvan_0944 | Rvan_0945 | Rvan_0944 | Rvan_0945 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.811 |
Rvan_0944 | Rvan_1051 | Rvan_0944 | Rvan_1051 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | PFAM: protein of unknown function DUF927; KEGG: esa:ESA_03018 hypothetical protein. | 0.906 |
Rvan_0944 | Rvan_1256 | Rvan_0944 | Rvan_1256 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | IstB domain protein ATP-binding protein; KEGG: bbt:BBta_p0100 putative insertion sequence IS21-like; putative ATP-binding protein; PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase. | 0.828 |
Rvan_0944 | Rvan_2446 | Rvan_0944 | Rvan_2446 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | IstB domain protein ATP-binding protein; KEGG: bbt:BBta_p0100 putative insertion sequence IS21-like; putative ATP-binding protein; PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase. | 0.828 |
Rvan_0944 | Rvan_2789 | Rvan_0944 | Rvan_2789 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | PFAM: protein of unknown function DUF927; KEGG: zinc-binding domain of primase-helicase family protein. | 0.906 |
Rvan_0944 | Rvan_3341 | Rvan_0944 | Rvan_3341 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Single-strand binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.816 |
Rvan_0944 | dnaA | Rvan_0944 | Rvan_0002 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.982 |
Rvan_0944 | dnaG | Rvan_0944 | Rvan_0309 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. | 0.992 |
Rvan_0944 | radA | Rvan_0944 | Rvan_0946 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.868 |
Rvan_0945 | Rvan_0944 | Rvan_0945 | Rvan_0944 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.811 |
Rvan_0945 | radA | Rvan_0945 | Rvan_0946 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. | 0.856 |
Rvan_1051 | Rvan_0944 | Rvan_1051 | Rvan_0944 | PFAM: protein of unknown function DUF927; KEGG: esa:ESA_03018 hypothetical protein. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.906 |
Rvan_1051 | Rvan_2789 | Rvan_1051 | Rvan_2789 | PFAM: protein of unknown function DUF927; KEGG: esa:ESA_03018 hypothetical protein. | PFAM: protein of unknown function DUF927; KEGG: zinc-binding domain of primase-helicase family protein. | 0.631 |
Rvan_1051 | dnaG | Rvan_1051 | Rvan_0309 | PFAM: protein of unknown function DUF927; KEGG: esa:ESA_03018 hypothetical protein. | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Belongs to the DnaG primase family. | 0.554 |
Rvan_1256 | Rvan_0944 | Rvan_1256 | Rvan_0944 | IstB domain protein ATP-binding protein; KEGG: bbt:BBta_p0100 putative insertion sequence IS21-like; putative ATP-binding protein; PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.828 |
Rvan_2446 | Rvan_0944 | Rvan_2446 | Rvan_0944 | IstB domain protein ATP-binding protein; KEGG: bbt:BBta_p0100 putative insertion sequence IS21-like; putative ATP-binding protein; PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.828 |
Rvan_2789 | Rvan_0944 | Rvan_2789 | Rvan_0944 | PFAM: protein of unknown function DUF927; KEGG: zinc-binding domain of primase-helicase family protein. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. | 0.906 |
Rvan_2789 | Rvan_1051 | Rvan_2789 | Rvan_1051 | PFAM: protein of unknown function DUF927; KEGG: zinc-binding domain of primase-helicase family protein. | PFAM: protein of unknown function DUF927; KEGG: esa:ESA_03018 hypothetical protein. | 0.631 |