STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Rvan_0984(NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. (823 aa)    
Predicted Functional Partners:
Rvan_0979
KEGG: alv:Alvin_2797 hydrogenase expression/formation protein HypE; TIGRFAM: hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein domain protein; AIR synthase related protein.
 
 
 0.997
Rvan_0977
KEGG: tmz:Tmz1t_3924 hydrogenase assembly chaperone HypC/HupF; TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC).
 
 
 0.942
Rvan_0978
KEGG: slt:Slit_2421 hydrogenase expression/formation protein HypD; TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; Belongs to the HypD family.
 
  
 0.942
Rvan_0976
KEGG: dda:Dd703_2527 hydrogenase accessory protein HypB; TIGRFAM: hydrogenase accessory protein HypB; PFAM: cobalamin synthesis protein P47K.
 
   
 0.923
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
   
 0.918
Rvan_0983
PFAM: nickel-dependent hydrogenase large subunit; KEGG: azo:azo3808 ferredoxin hydrogenase, large subunit.
 
 
 
 0.909
Rvan_0982
PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: azl:AZL_a10680 nickel-dependent hydrogenase small subunit.
 
 
 
 0.864
Rvan_0981
PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-4 domain protein; KEGG: PAS/PAC sensor signal transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; histidine kinase A domain protein.
     
 0.803
Rvan_0980
KEGG: mgm:Mmc1_2496 two component, sigma54 specific, fis family transcriptional regulator; PFAM: sigma-54 factor interaction domain-containing protein; response regulator receiver; helix-turn-helix Fis-type; SMART: response regulator receiver; AAA ATPase.
  
    0.671
Rvan_0289
PFAM: NADH-ubiquinone oxidoreductase chain 49kDa; KEGG: xau:Xaut_0170 NADH-ubiquinone oxidoreductase chain 49kDa.
     
 0.584
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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