Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rvan_1015KEGG: rpd:RPD_3337 sensory box histidine kinase/response regulator; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; response regulator receiver; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein. (713 aa)    
Predicted Functional Partners:
Rvan_1333
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.867
Rvan_0177
KEGG: rhi:NGR_c28760 putative two-component response regulator transcriptional regulatory protein; PFAM: response regulator receiver; SMART: response regulator receiver.
 
 
 0.765
Rvan_1016
KEGG: rpd:RPD_3338 hypothetical protein.
       0.757
Rvan_0927
Two component transcriptional regulator, winged helix family; KEGG: oca:OCAR_7111 cell cycle transcriptional regulator CtrA; PFAM: response regulator receiver; transcriptional regulator domain-containing protein; SMART: response regulator receiver.
 
   0.712
Rvan_3255
Integral membrane sensor signal transduction histidine kinase; KEGG: rpe:RPE_2289 periplasmic sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
  
     0.701
Rvan_0608
KEGG: bxe:Bxe_C0018 seriplasmic sensor signal transduction histidine kinase; PFAM: ATP-binding region ATPase domain protein; SMART: ATP-binding region ATPase domain protein.
  
     0.691
Rvan_2871
KEGG: cak:Caul_1496 response regulator receiver protein; PFAM: response regulator receiver; SMART: response regulator receiver.
 
 
   0.670
Rvan_2383
KEGG: histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
 
 
 0.657
Rvan_3256
GAF sensor signal transduction histidine kinase; KEGG: amc:MADE_03205 histidine kinase response regulator hybrid protein; PFAM: ATP-binding region ATPase domain protein; GAF domain protein; histidine kinase A domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; GAF domain protein.
 
 
 
0.628
Rvan_0143
PAS/PAC sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; histidine kinase A domain protein; response regulator receiver; KEGG: met:M446_1809 PAS/PAC sensor hybrid histidine kinase; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAC repeat-containing protein; PAS domain containing protein; response regulator receiver.
 
 
 
0.619
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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