Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rvan_1018Cyclic nucleotide-binding protein; KEGG: cbd:CBUD_1472 CAAX amino terminal protease family; PFAM: cyclic nucleotide-binding; Abortive infection protein; SMART: cyclic nucleotide-binding. (419 aa)    
Predicted Functional Partners:
Rvan_1333
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 
 0.767
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
   0.514
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.479
Rvan_3466
TIGRFAM: small GTP-binding protein; PFAM: Ras family protein; KEGG: chl:Chy400_1355 small GTP-binding protein; SMART: Ras small GTPase, Rab type.
    
  0.477
Rvan_1644
KEGG: xau:Xaut_0477 glutamate synthase (ferredoxin); PFAM: glutamine amidotransferase class-II; glutamate synthase; ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein.
     
 0.450
rpoC
DNA-directed RNA polymerase, beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.436
Rvan_1163
Putative adenylate/guanylate cyclase; PFAM: Tetratricopeptide TPR_1 repeat-containing protein; KEGG: rhi:NGR_b01410 probable adenylate class-3/4/guanylyl cyclase; SMART: Tetratricopeptide repeat.
  
 
 0.425
thrS
threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr).
  
    0.423
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
    
   0.413
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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