Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
Rvan_1041PFAM: protein of unknown function DUF323; KEGG: amr:AM1_G0021 hypothetical protein. (338 aa)    
Predicted Functional Partners:
Rvan_1262
PFAM: peptidase C14 caspase catalytic subunit p20; Tetratricopeptide TPR_1 repeat-containing protein; KEGG: mno:Mnod_2951 peptidase C14 caspase catalytic subunit P20.
     0.832
Rvan_3560
PFAM: sulfatase; KEGG: ava:Ava_0111 sulfatase.
 
   0.652
Rvan_2829
KEGG: app:CAP2UW1_2906 hypothetical protein.
  
     0.491
Rvan_1042
Oligopeptidase B; KEGG: oan:Oant_2691 oligopeptidase B; PFAM: peptidase S9A prolyl oligopeptidase domain protein beta-propeller.
       0.475
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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