Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
glnDUTP-GlnB uridylyltransferase, GlnD; SMART: metal-dependent phosphohydrolase HD region; TIGRFAM: protein-P-II uridylyltransferase; KEGG: UTP-GlnB uridylyltransferase, GlnD; PFAM: GlnD PII-uridylyltransferase; metal-dependent phosphohydrolase HD sub domain; amino acid-binding ACT domain protein. (917 aa)    
Predicted Functional Partners:
Rvan_0545
PFAM: nitrogen regulatory protein P-II; KEGG: pla:Plav_3243 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 
 0.974
glnE
(Glutamate--ammonia-ligase) adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal tra [...]
 
   
 0.848
Rvan_1135
Arsenate reductase-like protein; PFAM: arsenate reductase and related; KEGG: arsenate reductase and related protein; Belongs to the ArsC family.
       0.782
Rvan_1136
KEGG: msl:Msil_0360 RNA methyltransferase, TrmH family, group 3; TIGRFAM: RNA methyltransferase, TrmH family, group 3; PFAM: tRNA/rRNA methyltransferase (SpoU); RNA 2-O ribose methyltransferase substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
       0.762
Rvan_1137
PFAM: NUDIX hydrolase; KEGG: cai:Caci_0632 NUDIX hydrolase.
       0.762
Rvan_2230
PFAM: nitrogen regulatory protein P-II; KEGG: xau:Xaut_2209 nitrogen regulatory protein P-II; Belongs to the P(II) protein family.
 
 
 
 0.720
Rvan_1644
KEGG: xau:Xaut_0477 glutamate synthase (ferredoxin); PFAM: glutamine amidotransferase class-II; glutamate synthase; ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein.
     
 0.664
Rvan_1327
KEGG: bid:Bind_1518 signal transduction histidine kinase, nitrogen specific, NtrB; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold domain protein; SMART: ATP-binding region ATPase domain protein; histidine kinase A domain protein.
  
 
 
 0.657
Rvan_2229
KEGG: mex:Mext_2099 ammonium transporter; TIGRFAM: ammonium transporter; PFAM: ammonium transporter.
 
   
 0.597
Rvan_1139
Protein of unknown function DUF2126; KEGG: rpe:RPE_0086 transglutaminase domain-containing protein; PFAM: Protein of unknown function DUF2126; transglutaminase domain protein; transglutaminase domain-containing protein; SMART: transglutaminase domain-containing protein.
     
 0.596
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
Server load: low (30%) [HD]