Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Rvan_1419PFAM: N-6 DNA methylase; KEGG: rme:Rmet_6243 hypothetical protein. (253 aa)    
Predicted Functional Partners:
Rvan_2833
Restriction modification system DNA specificity domain protein; KEGG: ana:all2687 type I restriction-modification enzyme S subunit; manually curated; PFAM: restriction modification system DNA specificity domain.
 
 
 0.911
Rvan_2832
Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.855
Rvan_1906
PFAM: restriction modification system DNA specificity domain; KEGG: cli:Clim_2467 restriction modification system DNA specificity domain.
  
 
 0.808
Rvan_3142
PFAM: restriction modification system DNA specificity domain; KEGG: ava:Ava_3267 restriction modification system DNA specificity subunit.
  
 
 0.808
Rvan_1905
Type I site-specific deoxyribonuclease, HsdR family; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.714
Rvan_3141
PFAM: EcoEI R domain protein; type III restriction protein res subunit; protein of unknown function DUF450; KEGG: hsdR3; type I restriction-modification system RcaSBIV subunit R; SMART: DEAD-like helicase.
  
 
 0.670
Rvan_2831
PFAM: protein of unknown function DUF45; KEGG: bid:Bind_2675 hypothetical protein.
 
     0.629
Rvan_2836
KEGG: bid:Bind_2672 N-6 DNA methylase; TIGRFAM: type I restriction-modification system, M subunit; PFAM: N-6 DNA methylase.
  
     0.604
Rvan_0263
KEGG: mrd:Mrad2831_4673 putative DNA helicase.
  
  
 0.512
Rvan_1461
KEGG: pol:Bpro_1557 hypothetical protein.
  
    0.474
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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