STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rvan_1665PFAM: heat shock protein Hsp20; KEGG: bja:blr7961 HspC2 heat shock protein; Belongs to the small heat shock protein (HSP20) family. (168 aa)    
Predicted Functional Partners:
clpB
ATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
 
 
 0.671
Rvan_0347
TIGRFAM: ATP-dependent Clp protease, ATP-binding subunit clpA; PFAM: ATPase AAA-2 domain protein; Clp domain protein; AAA ATPase central domain protein; Clp ATPase-like; KEGG: ATP-dependent Clp protease, ATP-binding subunit ClpA; SMART: AAA ATPase; Belongs to the ClpA/ClpB family.
  
 
 0.616
Rvan_1785
KEGG: rpe:RPE_2641 ATPase; PFAM: ATPase AAA-2 domain protein; SMART: AAA ATPase.
  
 
 0.616
Rvan_1934
PFAM: Clp domain protein; KEGG: gga:396544 nascent polypeptide-associated complex alpha subunit.
  
 
 0.608
Rvan_1483
KEGG: sfu:Sfum_3853 hypothetical protein.
  
 
 0.587
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.581
Rvan_0340
PFAM: heat shock protein Hsp20; KEGG: mno:Mnod_1728 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.
  
  
 0.573
Rvan_3368
KEGG: oan:Oant_0492 HSP70 family protein.
  
 
 0.560
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.549
Rvan_1664
PFAM: alpha/beta hydrolase fold; KEGG: mxa:MXAN_6875 alpha/beta fold family hydrolase.
  
    0.547
Your Current Organism:
Rhodomicrobium vannielii
NCBI taxonomy Id: 648757
Other names: R. vannielii ATCC 17100, Rhodomicrobium vannielii ATCC 17100, Rhodomicrobium vannielii NCIMB 10020, Rhodomicrobium vannielii str. ATCC 17100, Rhodomicrobium vannielii strain ATCC 17100
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